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Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer
NCT00046904 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Etanercept is a substance that is being studied as a treatment for cachexia (weight loss) and anorexia (lack of appetite) in patients who have cancer. It is not yet known whether etanercept is effective in improving cancer-related cachexia and anorexia. PURPOSE: Randomized phase III trial to determine the effectiveness of etanercept in treating cancer-related cachexia and anorexia in patients who have advanced cancer.
Conditions Studied
Interventions
- BIOLOGICAL etanercept
Study Locations (19)
Iowa
- CCOP - Cedar Rapids Oncology Project — Cedar Rapids
- CCOP - Iowa Oncology Research Association — Des Moines
- Siouxland Hematology-Oncology Associates at June E. Nylen Cancer Center — Sioux City
Illinois
- CCOP - Illinois Oncology Research Association — Peoria
- CCOP - Carle Cancer Center — Urbana
South Dakota
- Rapid City Regional Hospital — Rapid City
- CCOP - Sioux Community Cancer Consortium — Sioux Falls
Alabama
- MBCCOP - Gulf Coast — Mobile
Arizona
- Mayo Clinic Scottsdale — Scottsdale
Florida
- Mayo Clinic - Jacksonville — Jacksonville
Hawaii
- MBCCOP - Hawaii — Honolulu
Kansas
- CCOP - Wichita — Wichita
Trial Details
| Field | Value |
|---|---|
| Start Date | 2003-05 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00046904
The ClinicalTrials.gov registry entry for NCT00046904 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Mayo Clinic, which has 3,246 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Unspecified Adult Solid Tumor, Protocol Specific appearing as the primary indexed condition, and to 1 intervention — of which etanercept is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00046904 reports 19 study locations spanning 15 distinct geographic areas — top geographies include Iowa, Illinois, South Dakota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00046904 about?
NCT00046904 is a clinical study titled "Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer". RATIONALE: Etanercept is a substance that is being studied as a treatment for cachexia (weight loss) and anorexia (lack of appetite) in patients who have cancer. It is not yet known whether etanercept is effective in improving cancer-related cachexia and anorexia. PURPOSE: Randomized phase III tria...
What is the current status of trial NCT00046904?
This trial is currently completed. It is a Phase 3 study. The study started on 2003-05.
What conditions does trial NCT00046904 study?
This clinical trial studies the following conditions: Unspecified Adult Solid Tumor, Protocol Specific, Cachexia, Anorexia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00046904?
The interventions under investigation include: etanercept (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00046904?
This trial is sponsored by Mayo Clinic, which has 3,246 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00046904 being conducted?
This trial has 19 study locations across Alabama, Arizona, Florida, Hawaii, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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