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NCT00042367 · ClinicalTrials.gov registry record · NA
Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors
A NA study of Brain Tumors, sponsored by Baylor College of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 119
- Enrollment target
- 3
- Study locations
NCT00042367: Completed NA study of Brain Tumors, sponsored by Baylor College of Medicine.
NCT00042367 is a NA study of Brain Tumors that has completed, run by Baylor College of Medicine. The registered enrollment target is 119 participants, below the 6,331-participant average among 10 other Brain Tumors trials with a reported enrollment target (98% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00042367, a NA study of Brain Tumors, has completed, sponsored by Baylor College of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 119 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purposes of this study are to find the highest dose of mafosfamide that can be given without causing severe side effects, to see how well the combination of these chemotherapy drugs and lower doses of radiation work to delay or stop the growth of the tumor, and to evaluate the pharmacokinetics (how the body handles) of Mafosfamide.
Primary Outcome
controlling the disease for at least 20 weeks.
Conditions Studied
Interventions
- DRUG Induction therapy (Regimen 1, Course 1, Cycle A1
- DRUG Regimen 1, Course 1, Cycle A2 (Days 22 - 42)
- DRUG Cycle B
- DRUG Regimen 1, Course 2
- DRUG Intrathecal Mafosfamide
Study Locations (3)
North Carolina
- Brain Tumor Center at Duke University - Durham
Tennessee
- St. Jude Children's Research Hospital - Memphis
Texas
- Texas Children's Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2000-04-04 |
| Est. Completion | 2006-06 |
| Phase | NA |
What the finished NCT00042367 record still lists
NCT00042367 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 6,331-participant average among 10 other Brain Tumors trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Brain Tumors appearing as the primary indexed condition, and to 5 interventions - of which Induction therapy (Regimen 1, Course 1, Cycle A1 is the first listed.
NCT00042367 reports a single indexed study location in North Carolina, Tennessee, Texas.
Frequently Asked Questions
What is clinical trial NCT00042367 about?
NCT00042367 is a clinical study titled "Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors". The purposes of this study are to find the highest dose of mafosfamide that can be given without causing severe side effects, to see how well the combination of these chemotherapy drugs and lower doses of radiation work to delay or stop the growth of the tumor, and to evaluate the pharmacokinetics (...
What is the current status of trial NCT00042367?
This trial is currently completed. It is a NA study. The enrollment target is 119 participants. The study started on 2000-04-04. Estimated completion is 2006-06.
What conditions does trial NCT00042367 study?
This clinical trial studies the following conditions: Brain Tumors.
What interventions are being tested in trial NCT00042367?
The interventions under investigation include: Induction therapy (Regimen 1, Course 1, Cycle A1 (DRUG), Regimen 1, Course 1, Cycle A2 (Days 22 - 42) (DRUG), Cycle B (DRUG), Regimen 1, Course 2 (DRUG), Intrathecal Mafosfamide (DRUG).
Who is sponsoring clinical trial NCT00042367?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00042367 being conducted?
This trial has 3 study locations across North Carolina, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00042367's enrollment target sits among peer trials
119 6th of 10 higher than 5 of 10 other Brain Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Florida Center for Brain Tumor Research
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ALA-induced PpIX Fluorescence During Brain Tumor Resection
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