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NCT00017628 · ClinicalTrials.gov registry record · Phase 1

Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis

A Phase 1 study of Multiple Sclerosis, sponsored by Northwestern Memorial Hospital.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target
2
Study locations

NCT00017628 is a Phase 1 study of Multiple Sclerosis that has completed, run by Northwestern Memorial Hospital. The registered enrollment target is 20 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT00017628, a Phase 1 study of Multiple Sclerosis, has completed, sponsored by Northwestern Memorial Hospital.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target
2
Study locations

Study Summary

OBJECTIVES: I. Determine the efficacy, in terms of disease progression, of high-dose cyclophosphamide and total body irradiation with T lymphocyte-depleted autologous peripheral blood stem cell or bone marrow rescue in patients with multiple sclerosis.

Conditions Studied

Multiple Sclerosis

Interventions

  • DRUG cyclophosphamide
  • DRUG methylprednisolone
  • DRUG filgrastim
  • PROCEDURE Autologous Stem Cell Transplantation

Study Locations (2)

Illinois

  • Northwestern Memorial Hospital - Chicago
  • Rush-Presbyterian-St. Luke's Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2001-04
Phase Phase 1

Sponsor

Northwestern Memorial Hospital

1 total trials

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What the Registry Record Tells You About NCT00017628

The ClinicalTrials.gov registry entry for NCT00017628 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower). The listed sponsor is Northwestern Memorial Hospital, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 4 interventions - of which cyclophosphamide is the first listed.

NCT00017628 reports 2 study locations spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00017628 about?

NCT00017628 is a clinical study titled "Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis". OBJECTIVES: I. Determine the efficacy, in terms of disease progression, of high-dose cyclophosphamide and total body irradiation with T lymphocyte-depleted autologous peripheral blood stem cell or bone marrow rescue in patients with multiple sclerosis.

What is the current status of trial NCT00017628?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2001-04.

What conditions does trial NCT00017628 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT00017628?

The interventions under investigation include: cyclophosphamide (DRUG), methylprednisolone (DRUG), filgrastim (DRUG), Autologous Stem Cell Transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00017628?

This trial is sponsored by Northwestern Memorial Hospital, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00017628 being conducted?

This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.