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NCT00017628 · ClinicalTrials.gov registry record · Phase 1
Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis
A Phase 1 study of Multiple Sclerosis, sponsored by Northwestern Memorial Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 2
- Study locations
NCT00017628: Completed Phase 1 study of Multiple Sclerosis, sponsored by Northwestern Memorial Hospital.
NCT00017628 is a Phase 1 study of Multiple Sclerosis that has completed, run by Northwestern Memorial Hospital. The registered enrollment target is 20 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00017628, a Phase 1 study of Multiple Sclerosis, has completed, sponsored by Northwestern Memorial Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
OBJECTIVES: I. Determine the efficacy, in terms of disease progression, of high-dose cyclophosphamide and total body irradiation with T lymphocyte-depleted autologous peripheral blood stem cell or bone marrow rescue in patients with multiple sclerosis.
Conditions Studied
Interventions
- DRUG cyclophosphamide
- DRUG methylprednisolone
- DRUG filgrastim
- PROCEDURE Autologous Stem Cell Transplantation
Study Locations (2)
Illinois
- Northwestern Memorial Hospital - Chicago
- Rush-Presbyterian-St. Luke's Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2001-04 |
| Phase | Phase 1 |
What the finished NCT00017628 record still lists
NCT00017628 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 4 interventions - of which cyclophosphamide is the first listed.
NCT00017628 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00017628 about?
NCT00017628 is a clinical study titled "Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis". OBJECTIVES: I. Determine the efficacy, in terms of disease progression, of high-dose cyclophosphamide and total body irradiation with T lymphocyte-depleted autologous peripheral blood stem cell or bone marrow rescue in patients with multiple sclerosis.
What is the current status of trial NCT00017628?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2001-04.
What conditions does trial NCT00017628 study?
This clinical trial studies the following conditions: Multiple Sclerosis.
What interventions are being tested in trial NCT00017628?
The interventions under investigation include: cyclophosphamide (DRUG), methylprednisolone (DRUG), filgrastim (DRUG), Autologous Stem Cell Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT00017628?
This trial is sponsored by Northwestern Memorial Hospital, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00017628 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00017628's enrollment target sits among peer trials
20 262nd of 315 higher than 41 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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