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NCT00008528 · ClinicalTrials.gov registry record · Phase 3

T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs

A Phase 3 study of HIV Infections, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 3
Development phase
525
Enrollment target
20
Study locations

NCT00008528: Completed Phase 3 study of HIV Infections, sponsored by Hoffmann-La Roche.

NCT00008528 is a Phase 3 study of HIV Infections that has completed, run by Hoffmann-La Roche. The registered enrollment target is 525 participants, above the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (18% higher). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00008528, a Phase 3 study of HIV Infections, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 3
Development phase
525 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to compare the change in viral load (amount of HIV in the blood) of patients who receive T-20 with selected anti-HIV drugs to that of patients who receive only selected anti-HIV drugs.

Conditions Studied

Interventions

  • DRUG Enfuvirtide

Study Locations (20)

California

  • Pacific Oaks Med Group - Beverly Hills
  • AIDS Healthcare Foundation - Los Angeles
  • Univ of California, San Diego - San Diego
  • San Francisco Gen Hosp - San Francisco
  • San Francisco VA Med Ctr - San Francisco

Massachusetts

  • New England Med Ctr - Boston
  • Massachusetts Gen Hosp - Boston
  • Community Research Initiative of New England - Brookline

Florida

  • IDC Research Initiative - Altamonte Springs
  • Steinhart Medical Associates - Miami

New York

  • Albany Med College - Albany
  • Peter Tsang - New York

Alabama

  • Univ of Alabama at Birmingham - Birmingham

Arizona

  • Phoenix Body Positive - Phoenix

Colorado

  • Univ of Colorado Health Sciences Ctr - Denver

District of Columbia

  • Whitman Walker Clinic/Elizabeth Taylor Med Ctr - Washington D.C.

Trial Details

FieldValue
Enrollment Target 525 participants
Phase Phase 3
Hoffmann-La Roche

909 total trials

What the finished NCT00008528 record still lists

NCT00008528 is an interventional study that assigns participants to a tested intervention. The registered 525 participants enrollment target is mid-sized for trials with a published cap, above the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (18% higher).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Enfuvirtide is the first listed.

NCT00008528 names 20 study sites across 12 states, led by California, Massachusetts, Florida.

Frequently Asked Questions

What is clinical trial NCT00008528 about?

NCT00008528 is a clinical study titled "T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs". The purpose of this study is to compare the change in viral load (amount of HIV in the blood) of patients who receive T-20 with selected anti-HIV drugs to that of patients who receive only selected anti-HIV drugs.

What is the current status of trial NCT00008528?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 525 participants.

What conditions does trial NCT00008528 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00008528?

The interventions under investigation include: Enfuvirtide (DRUG).

Who is sponsoring clinical trial NCT00008528?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00008528 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00008528's enrollment target sits among peer trials

525 59th of 542 higher than 483 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT00008528, the US trial registry maintained by the National Library of Medicine. NCT00008528 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.