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NCT00006411 · ClinicalTrials.gov registry record · NA
Cornea Donor Study
A NA study, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- NA
- Development phase
- 1,090
- Enrollment target
NCT00006411: Completed NA study, sponsored by National Eye Institute (NEI).
NCT00006411 is a NA study that has completed, run by National Eye Institute (NEI). The registered enrollment target is 1,090 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (22% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00006411, a NA study, has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- NA
- Development phase
- 1,090 participants
- Enrollment target
Study Summary
The Cornea Donor Study (CDS) was designed as a prospective cohort study with the following objectives: To determine whether the graft-failure rate over a 5-year follow-up period following corneal transplantation is the same when using corneal tissue from donors older than 65 years of age compared with tissue from younger donors. To assess the relationship between donor/recipient ABO blood type compatibility and graft failure due to rejection. To assess corneal endothelial cell density as an indicator of the health of the cornea and as a alternate outcome measure (in an optional Specular Microscopy Ancillary Study).
Primary Outcome
\# eyes with graft failure, defined as a regraft or a cloudy cornea that was sufficiently opaque as to compromise vision for a minimum of three consecutive months. Only one eye per participant was included in the study.
Interventions
- OTHER corneas assigned by donor age group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,090 participants |
| Start Date | 2000-01-10 |
| Est. Completion | 2014-07 |
| Phase | NA |
What the finished NCT00006411 record still lists
NCT00006411 is an interventional study that assigns participants to a tested intervention. Its 1,090 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (22% lower).
The record links to 0 conditions, and to 1 intervention - of which corneas assigned by donor age group is the first listed.
NCT00006411 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00006411 about?
NCT00006411 is a clinical study titled "Cornea Donor Study". The Cornea Donor Study (CDS) was designed as a prospective cohort study with the following objectives: To determine whether the graft-failure rate over a 5-year follow-up period following corneal transplantation is the same when using corneal tissue from donors older than 65 years of age compared w...
What is the current status of trial NCT00006411?
This trial is currently completed. It is a NA study. The enrollment target is 1,090 participants. The study started on 2000-01-10. Estimated completion is 2014-07.
What interventions are being tested in trial NCT00006411?
The interventions under investigation include: corneas assigned by donor age group (OTHER).
Who is sponsoring clinical trial NCT00006411?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00006411's enrollment target sits among peer trials
1,090 95th of 2000 higher than 1,906 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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