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NCT00005949 · ClinicalTrials.gov registry record · Phase 2

Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma

A Phase 2 study of Recurrent Melanoma and Stage IV Melanoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT00005949: Completed Phase 2 study of Recurrent Melanoma and Stage IV Melanoma, sponsored by National Cancer Institute (NCI).

NCT00005949 is a Phase 2 study of Recurrent Melanoma and Stage IV Melanoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 50 participants, below the 171-participant average among 23 other Recurrent Melanoma trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005949, a Phase 2 study of Recurrent Melanoma and Stage IV Melanoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

Phase II trial to study the effectiveness of vaccine therapy plus interleukin-2 in treating patients who have advanced melanoma. Vaccines made from a person's cancer cells may make the body build an immune response to kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Melanoma vaccine plus interleukin-2 may kill more cancer cells

Conditions Studied

Recurrent Melanoma Stage IV Melanoma

Interventions

  • OTHER laboratory biomarker analysis
  • BIOLOGICAL aldesleukin
  • BIOLOGICAL gp100:209-217(210M) peptide vaccine

Study Locations (1)

Illinois

  • Cancer and Leukemia Group B - Chicago

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2001-03
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00005949 record still lists

NCT00005949 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 171-participant average among 23 other Recurrent Melanoma trials with a reported enrollment target (71% lower).

The record links to 2 conditions, with Recurrent Melanoma appearing as the primary indexed condition, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT00005949 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT00005949 about?

NCT00005949 is a clinical study titled "Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma". Phase II trial to study the effectiveness of vaccine therapy plus interleukin-2 in treating patients who have advanced melanoma. Vaccines made from a person's cancer cells may make the body build an immune response to kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill...

What is the current status of trial NCT00005949?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2001-03.

What conditions does trial NCT00005949 study?

This clinical trial studies the following conditions: Recurrent Melanoma, Stage IV Melanoma.

What interventions are being tested in trial NCT00005949?

The interventions under investigation include: laboratory biomarker analysis (OTHER), aldesleukin (BIOLOGICAL), gp100:209-217(210M) peptide vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00005949?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00005949 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Recurrent Melanoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00005949's enrollment target sits among peer trials

50 11th of 23 higher than 12 of 23 other Recurrent Melanoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Recurrent Melanoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT00005949, the US trial registry maintained by the National Library of Medicine. NCT00005949 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.