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NCT00003235 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Can Not Be Surgically Removed

A Phase 3 study, sponsored by Eastern Cooperative Oncology Group.

Completed
Registry status
Phase 3
Development phase
294
Enrollment target

NCT00003235: Completed Phase 3 study, sponsored by Eastern Cooperative Oncology Group.

NCT00003235 is a Phase 3 study that has completed, run by Eastern Cooperative Oncology Group. The registered enrollment target is 294 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003235, a Phase 3 study, has completed, sponsored by Eastern Cooperative Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
294 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug with either standard radiation therapy or radiation therapy given at different times may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy consisting of paclitaxel and carboplatin, plus either standard radiation therapy or radiation therapy given at different times, in treating patients with stage III non-small cell lung cancer that cannot be surgically removed.

Interventions

  • DRUG carboplatin
  • DRUG paclitaxel
  • RADIATION radiation therapy

Trial Details

FieldValue
Enrollment Target 294 participants
Start Date 1998-06-01
Phase Phase 3
Eastern Cooperative Oncology Group

141 total trials

What the finished NCT00003235 record still lists

NCT00003235 is an interventional study that assigns participants to a tested intervention. The registered 294 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 3 interventions - of which carboplatin is the first listed.

NCT00003235 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003235 about?

NCT00003235 is a clinical study titled "Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Can Not Be Surgically Removed". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug with either standard radiation therapy or radiation therapy given at different times m...

What is the current status of trial NCT00003235?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 294 participants. The study started on 1998-06-01.

What interventions are being tested in trial NCT00003235?

The interventions under investigation include: carboplatin (DRUG), paclitaxel (DRUG), radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT00003235?

This trial is sponsored by Eastern Cooperative Oncology Group, which has 141 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003235's enrollment target sits among peer trials

294 1166th of 2000 higher than 835 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003235, the US trial registry maintained by the National Library of Medicine. NCT00003235 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.