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NCT00001491 · ClinicalTrials.gov registry record
Analysis of the Nervous System in Patients With Fabry's Disease
A clinical trial of Fabry's Disease, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 325
- Enrollment target
- 1
- Study location
NCT00001491 is a study of Fabry's Disease that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 325 participants. The trial reports 1 study location across 1 state.
The verdict
NCT00001491, a study of Fabry's Disease, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 325 participants
- Enrollment target
- 1
- Study location
Study Summary
Fabry's disease a genetic disorder (X-linked recessive) due to the absence of the enzyme ceramidetrihexosidase. The disease is characterized by abnormal collections of glycolipids in cells (histiocytes) within blood vessel walls, tumors on the thighs, buttocks, and genitalia, decreased sweating, tingling sensations in the extremities, and cataracts. Patients with Fabry 's disease die from complications of the kidney, heart, or brain. The purpose of this study is to measure levels of a protein marker (PGP 9.5) in the skin, blood, and fluid surrounding the brain and spinal cord (CSF) in patients with Fabry's disease. In addition the study will attempt to determine if levels of the protein are directly related to the severity of disease in the nervous system. PGP 9.5 protein levels will be measured in normal volunteers and patients with other diseases of the nervous system then compared to the levels recorded in patients with Fabry's disease. This research study is designed to improve the understanding of Fabry's disease. Patients participating in it will not directly benefit from it. However, knowledge gained as a result of this study may contribute to the development of effective therapies for Fabry's disease.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 325 participants |
| Start Date | 1995-05-11 |
| Est. Completion | 2008-03-03 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001491
The ClinicalTrials.gov registry entry for NCT00001491 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 325 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Fabry's Disease appearing as the primary indexed condition, and to 0 interventions.
NCT00001491 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001491 about?
NCT00001491 is a clinical study titled "Analysis of the Nervous System in Patients With Fabry's Disease". Fabry's disease a genetic disorder (X-linked recessive) due to the absence of the enzyme ceramidetrihexosidase. The disease is characterized by abnormal collections of glycolipids in cells (histiocytes) within blood vessel walls, tumors on the thighs, buttocks, and genitalia, decreased sweating, tin...
What is the current status of trial NCT00001491?
This trial is currently completed. The enrollment target is 325 participants. The study started on 1995-05-11. Estimated completion is 2008-03-03.
What conditions does trial NCT00001491 study?
This clinical trial studies the following conditions: Fabry's Disease.
Who is sponsoring clinical trial NCT00001491?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001491 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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