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NCT03341754 · ClinicalTrials.gov registry record · Phase 1

Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults

A Phase 1 study, sponsored by U.S. Army Medical Research and Development Command.

Completed
Registry status
Phase 1
Development phase
52
Enrollment target

NCT03341754 is a Phase 1 study that has completed, run by U.S. Army Medical Research and Development Command. The registered enrollment target is 52 participants.

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The verdict

NCT03341754, a Phase 1 study, has completed, sponsored by U.S. Army Medical Research and Development Command.

COMPLETED
Registry status
Phase 1
Development phase
52 participants
Enrollment target

Study Summary

This is a study designed to assess the safety, tolerability, immunogenicity, and protective efficacy of 2 heterologous prime-boost vaccine regimens in healthy, malaria naïve adults. The study will include 2 vaccine groups and an infectivity control (IC) group consisting of non-immunized subjects. Subjects to be immunized will be randomly assigned to one of two vaccine groups.

Interventions

  • BIOLOGICAL D/ChAd63-CA
  • BIOLOGICAL D/ChAd63-CAT
  • OTHER Infectivity Control (IC) Group

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2018-09-15
Est. Completion 2020-03-23
Phase Phase 1

What the Registry Record Tells You About NCT03341754

The ClinicalTrials.gov registry entry for NCT03341754 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is U.S. Army Medical Research and Development Command, which has 77 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which D/ChAd63-CA is the first listed.

NCT03341754 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03341754 about?

NCT03341754 is a clinical study titled "Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults". This is a study designed to assess the safety, tolerability, immunogenicity, and protective efficacy of 2 heterologous prime-boost vaccine regimens in healthy, malaria naïve adults. The study will include 2 vaccine groups and an infectivity control (IC) group consisting of non-immunized subjects. Su...

What is the current status of trial NCT03341754?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2018-09-15. Estimated completion is 2020-03-23.

What interventions are being tested in trial NCT03341754?

The interventions under investigation include: D/ChAd63-CA (BIOLOGICAL), D/ChAd63-CAT (BIOLOGICAL), Infectivity Control (IC) Group (OTHER).

Who is sponsoring clinical trial NCT03341754?

This trial is sponsored by U.S. Army Medical Research and Development Command, which has 77 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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