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NCT04688632 · ClinicalTrials.gov registry record · Phase 1
Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects
A Phase 1 study, sponsored by Theravance Biopharma.
- Completed
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
NCT04688632: Completed Phase 1 study, sponsored by Theravance Biopharma.
NCT04688632 is a Phase 1 study that has completed, run by Theravance Biopharma. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04688632, a Phase 1 study, has completed, sponsored by Theravance Biopharma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
Study Summary
A double-blind study to characterize the effect of ampreloxetine on cardiac repolarization in healthy subjects.
Primary Outcome
Change in QTcF from baseline
Interventions
- DRUG Moxifloxacin
- DRUG Moxifloxacin Placebo
- DRUG Ampreloxetine <Dose A>
- DRUG Ampreloxetine <Dose B>
- DRUG Ampreloxetine Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2021-01-18 |
| Est. Completion | 2021-03-26 |
| Phase | Phase 1 |
What the finished NCT04688632 record still lists
NCT04688632 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).
The record links to 0 conditions, and to 5 interventions - of which Moxifloxacin is the first listed.
NCT04688632 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04688632 about?
NCT04688632 is a clinical study titled "Thorough QT Study to Evaluate Ampreloxetine in Healthy Subjects". A double-blind study to characterize the effect of ampreloxetine on cardiac repolarization in healthy subjects.
What is the current status of trial NCT04688632?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2021-01-18. Estimated completion is 2021-03-26.
What interventions are being tested in trial NCT04688632?
The interventions under investigation include: Moxifloxacin (DRUG), Moxifloxacin Placebo (DRUG), Ampreloxetine <Dose A> (DRUG), Ampreloxetine <Dose B> (DRUG), Ampreloxetine Placebo (DRUG).
Who is sponsoring clinical trial NCT04688632?
This trial is sponsored by Theravance Biopharma, which has 38 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04688632's enrollment target sits among peer trials
72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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