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NCT03432793 · ClinicalTrials.gov registry record · Phase 1

Drug-Drug Interaction (DDI) Study for TD-9855

A Phase 1 study of Drug-Drug Interaction (DDI), sponsored by Theravance Biopharma.

Completed
Registry status
Phase 1
Development phase
41
Enrollment target
1
Study location

NCT03432793 is a Phase 1 study of Drug-Drug Interaction (DDI) that has completed, run by Theravance Biopharma. The registered enrollment target is 41 participants, roughly in line with the 43-participant average among 3 other Drug-Drug Interaction (DDI) trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT03432793, a Phase 1 study of Drug-Drug Interaction (DDI), has completed, sponsored by Theravance Biopharma.

COMPLETED
Registry status
Phase 1
Development phase
41 participants
Enrollment target
1
Study location

Study Summary

This study is designed to assess the effect of fluvoxamine, itraconazole and smoking on the PK disposition of multiple doses TD-9855 in healthy male subjects. The study will also assess the relationship between caffeine PK and TD-9855 PK disposition in healthy male smokers and non-smokers.

Interventions

  • DRUG Itraconazole
  • DRUG Caffeine
  • DRUG Fluvoxamine
  • DRUG TD-9855

Study Locations (1)

Nebraska

  • Celerion - Lincoln

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2018-02-28
Est. Completion 2018-04-21
Phase Phase 1

Sponsor

Theravance Biopharma

38 total trials

What the Registry Record Tells You About NCT03432793

The ClinicalTrials.gov registry entry for NCT03432793 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 43-participant average among 3 other Drug-Drug Interaction (DDI) trials with a reported enrollment target. The listed sponsor is Theravance Biopharma, which has 38 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Drug-Drug Interaction (DDI) appearing as the primary indexed condition, and to 4 interventions - of which Itraconazole is the first listed.

NCT03432793 reports 1 study location spanning 1 distinct geographic area - top geographies include Nebraska.

Frequently Asked Questions

What is clinical trial NCT03432793 about?

NCT03432793 is a clinical study titled "Drug-Drug Interaction (DDI) Study for TD-9855". This study is designed to assess the effect of fluvoxamine, itraconazole and smoking on the PK disposition of multiple doses TD-9855 in healthy male subjects. The study will also assess the relationship between caffeine PK and TD-9855 PK disposition in healthy male smokers and non-smokers.

What is the current status of trial NCT03432793?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2018-02-28. Estimated completion is 2018-04-21.

What conditions does trial NCT03432793 study?

This clinical trial studies the following conditions: Drug-Drug Interaction (DDI).

What interventions are being tested in trial NCT03432793?

The interventions under investigation include: Itraconazole (DRUG), Caffeine (DRUG), Fluvoxamine (DRUG), TD-9855 (DRUG).

Who is sponsoring clinical trial NCT03432793?

This trial is sponsored by Theravance Biopharma, which has 38 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03432793 being conducted?

This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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