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NCT03556592 · ClinicalTrials.gov registry record · Phase 1

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

A Phase 1 study, sponsored by LEO Pharma.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT03556592 is a Phase 1 study that has completed, run by LEO Pharma. The registered enrollment target is 40 participants.

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The verdict

NCT03556592, a Phase 1 study, has completed, sponsored by LEO Pharma.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this trial is to investigate if tralokinumab changes the metabolism of selected CYP substrates in adults with moderate-to-severe AD after: * 14 weeks of treatment with tralokinumab * a single dose of tralokinumab

Interventions

  • DRUG Omeprazole
  • DRUG Tralokinumab
  • DRUG Caffeine
  • DRUG Warfarin
  • DRUG Metoprolol

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2018-08-13
Est. Completion 2020-06-20
Phase Phase 1

Sponsor

LEO Pharma

65 total trials

What the Registry Record Tells You About NCT03556592

The ClinicalTrials.gov registry entry for NCT03556592 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is LEO Pharma, which has 65 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Omeprazole is the first listed.

NCT03556592 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03556592 about?

NCT03556592 is a clinical study titled "Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4". The purpose of this trial is to investigate if tralokinumab changes the metabolism of selected CYP substrates in adults with moderate-to-severe AD after: * 14 weeks of treatment with tralokinumab * a single dose of tralokinumab

What is the current status of trial NCT03556592?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2018-08-13. Estimated completion is 2020-06-20.

What interventions are being tested in trial NCT03556592?

The interventions under investigation include: Omeprazole (DRUG), Tralokinumab (DRUG), Caffeine (DRUG), Warfarin (DRUG), Metoprolol (DRUG).

Who is sponsoring clinical trial NCT03556592?

This trial is sponsored by LEO Pharma, which has 65 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.