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Find a clinical trial that's recruiting now
Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.
- 24,857
- trials recruiting now
- 14%
- of all US trials open to enrollment
- 52
- states with recruiting sites
A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.
Popular conditions
50 trials found
Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver)
Johns Hopkins University
This research is being done to better understand opportunistic infections and cancer in transplant recipients with HIV who receive livers from a donor with HIV compared to livers from donors without HIV.
NCT07665372
Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients
National Institute of Allergy and Infectious Diseases (NIAID)
To compare the efficacy of oral sorivudine (brovavir) and oral acyclovir for the treatment of localized herpes zoster in HIV-infected patients. HIV-infected patients are at high risk for herpesvirus infections...
NCT00000953
Trichomonas Vaginalis Repeat Infections Among HIV Negative Women
Tulane University Health Sciences Center
The overall goal of this project is to determine the influence of patient treatment and host factors on repeat Trichomonas vaginalis (TV) infections among HIV-negative women
NCT01832480
A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive Medications
National Institute of Allergy and Infectious Diseases (NIAID)
...Children have been receiving medications to prevent complications of HIV infection, such as Pneumocystis carinii pneumonia (PCP), Mycobacterium avium complex (MAC) disease, or other bacterial infections. It is common for HIV-positive...
NCT00001078
When to Start Anti-HIV Drugs in Patients With Opportunistic Infections
National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to evaluate the effect of starting anti-HIV drugs in HIV infected patients who are being treated for opportunistic infections (OIs). This study will follow two...
NCT00055120
A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common
Pfizer
To compare the efficacy of fluconazole versus placebo in preventing the development of active coccidioidomycosis and other systemic fungal infections among HIV-infected patients with CD4 lymphocyte counts \< 250 cells/mm3 who...
NCT00002325
Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs
National Institute of Allergy and Infectious Diseases (NIAID)
...Pneumococcal infections are the most common AIDS-related infection in HIV-infected children. PCV may help reduce the chances of HIV-infected children getting pneumococcal infections. This study will look at whether...
NCT00013871
A Study of Peer Education to Prevent HIV Transmission Among Injection Drug Users and Their HIV Risk Contacts
National Institute of Allergy and Infectious Diseases (NIAID)
...Studies have shown that peer education programs can reduce HIV risk behavior in IDUs. However, it is not known if reduced HIV risk behavior leads to fewer HIV infections. The purpose of...
NCT00038688
Evaluate Tolerability of a Multi-envelope, Prime-boost HIV Vaccine in Healthy Adults
St. Jude Children's Research Hospital
...Due to the success in treating other viral infections, scientists are trying to develop a vaccine for human immunodeficiency virus (HIV). HIV infection is the cause of acquired immune deficiency syndrome (AIDS...
NCT00623753
Behavioral Intervention to Enhance HIV Test/Treat
University of Connecticut
Prevention strategies that aim to test and treat people for HIV infection are undermined by HIV treatment non-adherence and sexually transmitted co-infections (STI). The proposed study will test a theory...
NCT01752777
Acute HIV Infection Observational Study
National Institute of Allergy and Infectious Diseases (NIAID)
...Data from this study will be used to better understand properties of HIV, including HIV transmission and the differences between acute and established HIV infections.
NCT00296660
Development and Pilot Testing of a PHCI for Emergency Department Patients Who Decline Rapid HIV/ HCV Screening
Rhode Island Hospital
...Screening for both infections in EDs is preferable due to: the shared overlap of some risk behaviors for HIV and HCV acquisition (e.g., drug use) the relatively high co-occurrence of...
NCT04137094
HIV Prevention for African American Teens
Emory University
AFIYA aims to reduce both the risk of Sexually Transmitted Infections (STIs) and HIV in young African American females through a culturally and gender appropriate intervention (group sessions) coupled with an individualized...
NCT00279799
HIV Oral Testing Infographic Experiment
New York University
Premised on the National AIDS Strategy's focus on identifying new HIV infections through increased HIV testing, the purpose of this formative pilot study is to develop and test an integrated HIV...
NCT04061915
Study of Women Who Have AIDS
National Institute of Allergy and Infectious Diseases (NIAID)
...To study the effect of HIV disease on gynecologic health including infections and reproductive function.
NCT00001050
The Safety and Effectiveness of a Two-Drug Combination in the Treatment of Patients With Hepatitis C Plus Advanced HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
...To determine the efficacy of treatment with IFN alfa-2b for chronic hepatitis C in patients with advanced HIV infections treated with nucleoside analog therapy. IFN alfa-2b has HIV inhibitory properties...
NCT00001035
MyPEEPS LITE Trial
Columbia University
...HIV infections occurs in the context of potential multilevel moderators and conceptual mediators. This is key to advancing HIV prevention among HIV-negative US persons at extremely high-risk for HIV seroconversion.
NCT06741631
Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in Men
National Institute of Allergy and Infectious Diseases (NIAID)
...to determine whether daily use of emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) can prevent HIV infection in men who also receive HIV counseling, condoms, and treatment for other sexually transmitted infections (STIs).
NCT00458393
A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection
National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to understand how changes in the immune system of HIV-infected patients affect their risk for 3 serious infections: Pneumocystis carinii pneumonia (PCP), cytomegalovirus (CMV) retinitis...
NCT00005572
Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
...Anti-HIV therapy may increase CD4 counts, which may lead to a decrease in AIDS-related infections. Problems that anti-HIV therapy is associated with include metabolic problems, neurologic problems, abnormal opportunistic...
NCT00000883
Gene Expression in HIV and Tuberculosis Co-infection
National Institute of Allergy and Infectious Diseases (NIAID)
Background: \- Tuberculosis (TB) infection is particularly deadly when it happens in people who are also infected with the human immunodeficiency virus (HIV). However, not much is known about how these two infections...
NCT01611402
Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV
Aaron Diamond AIDS Research Center
To demonstrate, in patients with tubercular or nontubercular mycobacterium infections with or without HIV infection, the safety of thalidomide use as judged by symptoms, physical exam, and studies of microbiologic, immunologic, hematologic...
NCT00002104
Safety of and Immune Response to an H1N1 Influenza Virus Vaccine in HIV Infected Children and Youth
National Institute of Allergy and Infectious Diseases (NIAID)
Children and people infected with HIV are particularly susceptible to influenza infections. This study testED the safety and effectiveness of a vaccine for the new H1N1 influenza virus in children and youth...
NCT00992836
A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
National Institute of Allergy and Infectious Diseases (NIAID)
This study compares 2 different treatments administered to try to prevent serious bacterial infections (such as pneumonia) in HIV-positive children. A combination of drugs (azithromycin plus atovaquone) will be compared to...
NCT00000811
Trauma-informed Care for Youth With HIV in Memphis
Meharry Medical College
...for both youth with HIV and their HIV care providers in the priority region of Memphis, TN, which houses the third highest rate of new HIV infections, with a third among youth.
NCT07137026
The Women's HIV SeroIncidence Study (ISIS)
HIV Prevention Trials Network
Approximately 30 percent of new HIV infections in the Unites States occur in women, with a disproportionate number occurring in women of color. This observational study has been designed to help determine...
NCT00995176
Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women
National Institute of Allergy and Infectious Diseases (NIAID)
...risk of vaginal infections. Participants will include 234 women who are sexually active (greater than or equal to 4 episodes of sex with men during the past month), HIV-negative, 18 to...
NCT01230814
Screening HIV-Infected Patients for Vaccine Studies
National Institute of Allergy and Infectious Diseases (NIAID)
This screening study will evaluate potential study volunteers with HIV infection to see if they are suitable candidates for trials of experimental vaccines against HIV (therapeutic), and against other infections (preventive). * Preventive...
NCT00051519
Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV
University of California, Los Angeles
...which post-exposure prophylaxis (medicines that may help prevent HIV infection after an exposure) can be a part. It will also include risk reduction information and testing for other sexually transmitted infections.
NCT00949234
A Study to Evaluate the Effects of Interleukin-12 (rhIL-12) in HIV-Positive Patients With CD4 Cell Counts Less Than 50 Cells/mm3 or 300-500 Cells/mm3
National Institute of Allergy and Infectious Diseases (NIAID)
...This study will look at the ability of rhIL-12 to boost the immune system against HIV and HIV-associated bacterial infections in these patients. IL-12 is found naturally in the...
NCT00000857
Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV
Louisiana State University Health Sciences Center in New Orleans
...The secondary objectives of the study are to observe short term clinical outcomes of prevalent HPV genotype-specific anogenital infections in adults living with HIV who complete the three-dose Gardasil-9...
NCT05266898
The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms
National Institute of Allergy and Infectious Diseases (NIAID)
...AZT has been shown to decrease the mortality and the frequency of opportunistic infections in certain adult patients with symptomatic HIV infection. It is, therefore, likely that symptomatic HIV-infected children may...
NCT00000990
Sexually Transmitted Infections Among African American Women Who Have Sex With Women
University of Mississippi Medical Center
The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW). The first study...
NCT01043081
Lung HIV Disease in a Large Cohort-Pitt
University of Pittsburgh
...of emphysema compared to non-HIV-infected patients, and it has been hypothesized that this accelerated disease progression is the result of one or more latent infections that amplifies the pulmonary inflammatory...
NCT01326572
Evaluating the Safety and Drug Levels of an Antibody Against HIV in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
Antibodies are natural proteins that the body makes to fight infections. Antibodies can also be manufactured like a drug and infused or injected into the body to prevent or treat a disease...
NCT02165267
Prescribe to Prevent HIV: A Hybrid Trial Helping Addiction Clinics Prevent HIV & Infections Through Safer Drug Use Support
University of Pittsburgh
In the U.S., an estimated 3.6 million people who inject drugs (PWID) face a growing yet preventable health crisis, with rising cases of serious injection-related infections (SIRI), including HIV...
NCT07073924
Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV)
National Heart, Lung, and Blood Institute (NHLBI)
The Lung HIV goal is to facilitate the data and specimen collection efforts of eight individual HIV and pulmonary studies that operate under the direction of the NHLBI. The Lung HIV study...
NCT00933595
A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients
Pfizer
...Mycobacterium avium Complex (MAC) infection in HIV-infected patients. To determine the efficacy of daily versus weekly fluconazole for the prevention of deep fungal infections in this patient population. SECONDARY: To determine...
NCT00002122
COVID-19 in Patients With HIV
University of Missouri-Columbia
...People with HIV who have not achieved viral suppression through antiretroviral treatment may have a compromised immune system that leaves them vulnerable to infections and disease progression. However, little is known about...
NCT04333953
A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
Glaxo Wellcome
To determine the safety and efficacy of oral valacyclovir hydrochloride ( 256U87 ) compared to acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients with CD4 counts = or \> 100 cells/mm3.
NCT00002084
Hormonal Birth Control and the Risk of Acquiring HIV
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
...Sexual intercourse between men and women is the main way HIV is transmitted. About 90 percent of HIV infections in women are caused by sexual intercourse. Also, hormonal birth controls are widely...
NCT00006324
Factors Predicting Persistence of Oncogenic HPV and Cervical Dysplasia in HIV Infected Kenyan Women
Indiana University
This study will utilize a longitudinal study design to better understand the natural history of oncogenic Human Papillomavirus (HPV) infections in Human Immunodeficiency Virus (HIV)-infected and HIV-uninfected Kenyan women, including...
NCT04045652
Stigma and Online Counseling to Increase HIV/STI Testing
University of Connecticut
The alarmingly high rates of HIV/STI (sexually transmitted infections) observed among Black men who have sex with men (BMSM) necessitate a new model for engaging BMSM. New approaches include addressing stigma...
NCT03107910
Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care
National Institute of Allergy and Infectious Diseases (NIAID)
Many HIV infected patients admitted to the intensive care area (ICA) have never taken anti-HIV drugs. The purpose of this study is to learn whether starting anti-HIV drugs while patients...
NCT00028327
Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and Women
National Institute of Allergy and Infectious Diseases (NIAID)
Men who have sex with men (MSM) have an increased risk of developing anal human papillomavirus (HPV) infections, which can be a risk factor for anal cancer. HIV-infected women are also...
NCT01461096
Problems With Immune Recovery in the Gut Tissue
University of Minnesota
...of HIV replication in the lymph tissue and gut tissue of people taking HIV drugs causes long-term damage to the ability of the gut to protect you from other infections and...
NCT01460433
Directly Observed Therapy for HIV Infected Adolescents
National Institute of Allergy and Infectious Diseases (NIAID)
...determine the effectiveness of a new DOT strategy in HIV infected adolescents who have had difficulty adhering to anti-HIV drug regimens or regimens to prevent opportunistic infections (OIs) in the past.
NCT00259389
The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders
Columbia University
The proposed study addresses a significant public health threat of Human immunodeficiency virus (HIV) and sexually transmitted infections (STIs) among drug involved women on probation, parole or other community supervision. This randomized...
NCT01784809
A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients
Glaxo Wellcome
To evaluate the safety and efficacy of oral valacyclovir hydrochloride (256U87) vs. acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients (CD4 greater than or equal to 100).
NCT00002000
A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
National Institute of Allergy and Infectious Diseases (NIAID)
...Persons with HIV disease who are receiving AZT are at risk for PCP, toxoplasmosis, bacterial pneumonia, and other serious infections. It is therefore important to find drugs that can be given along...
NCT00000991
Read our methodology - how recruiting status is sourced and refreshed from the public registry.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.