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ClinicalTrials.gov 1 recruiting now official registry

Stage IV Lung Non-Small Cell Cancer AJCC v7 clinical trials

1 of 8 indexed Stage IV Lung Non-Small Cell Cancer AJCC v7 trials are currently recruiting.

8 US clinical trials · 1 currently recruiting

Stage IV Lung Non-Small Cell Cancer AJCC v7 is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 6 of these trials.

The research picture

Stage IV Lung Non-Small Cell Cancer AJCC v7 has 8 registered US clinical trials, 1 of them open to new participants right now, about 13% of the total.

1
recruiting participants now
13%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
6
top sponsor: National Cancer Institute (NCI)
Phase 14Phase 24

Active & Recent Trials

8 total, page 1 of 1

RECRUITING Phase 2 46 participants

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

National Cancer Institute (NCI)

NCT03191149

ACTIVE NOT RECRUITING Phase 1 126 participants

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

NCT02444741

ACTIVE NOT RECRUITING Phase 2 125 participants

Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT01708954

ACTIVE NOT RECRUITING Phase 2 110 participants

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT02888743

ACTIVE NOT RECRUITING Phase 2 60 participants

Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT02642042

ACTIVE NOT RECRUITING Phase 1 37 participants

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

M.D. Anderson Cancer Center

NCT02321501

ACTIVE NOT RECRUITING Phase 1 36 participants

Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT02503722

COMPLETED Phase 1 11 participants

Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer

National Cancer Institute (NCI)

NCT02535338

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage IV Lung Non-Small Cell Cancer AJCC v7 Trial Landscape

8 indexed Stage IV Lung Non-Small Cell Cancer AJCC v7 studies · 1 recruiting (13%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: National Cancer Institute (NCI) (6 trials), 1 other listed. 8 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage IV Lung Non-Small Cell Cancer AJCC v7?

PlainTrial tracks 8 US clinical trials for Stage IV Lung Non-Small Cell Cancer AJCC v7, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage IV Lung Non-Small Cell Cancer AJCC v7?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.