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Social Anxiety Disorder (SAD) clinical trials
Every US clinical trial registered for Social Anxiety Disorder (SAD) — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
6 US clinical trials · 4 currently recruiting
The research picture
Social Anxiety Disorder (SAD) has 6 registered US clinical trials, 4 of them open to new participants right now — about 67% of the total.
- 4
- recruiting participants now
- 67%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Engrail Therapeutics
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder
Vanda Pharmaceuticals
NCT07221578
Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)
VistaGen Therapeutics
NCT06615557
Stepped Care Treatment for Anxiety Resilience
Andrew Wiese
NCT07228143
A Study of NTX-1472 in Social Anxiety Disorder
Newleos Therapeutics
NCT07323784
A Study to Evaluate the Efficacy and Safety of ENX-102 in Participants With Social Anxiety Disorder
Engrail Therapeutics
NCT07193563
Nefazodone in the Treatment of Social Phobia
Emory University
NCT00231348
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Social Anxiety Disorder (SAD) Trial Landscape
ClinicalTrials.gov lists 6 US studies indexed under Social Anxiety Disorder (SAD), and 4 of those are currently open to recruitment — roughly 67% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Social Anxiety Disorder (SAD) shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Social Anxiety Disorder (SAD) is led by Engrail Therapeutics with 1 indexed trial, alongside 5 other organizations in the top contributor list. The list on this page surfaces up to 6 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Social Anxiety Disorder (SAD)?
PlainTrial tracks 6 US clinical trials for Social Anxiety Disorder (SAD), of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Social Anxiety Disorder (SAD)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.