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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Refractory Angina: early-phase trial registry

2 of 3 indexed Refractory Angina trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #5,209 of 28,707 conditions by registered trial count.

3 US clinical trials · 2 currently recruiting · #5,209 of 28,707 conditions by registered trial count

Refractory Angina: 3 US clinical trials tracked, 2 recruiting.

Refractory Angina is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Shockwave Medical, running 1 of these trials.

Enrollment posture brief

Registry condition refractory-angina

OPEN 2 | RECR 67% | LATE 0 | EARLY 1 | RANK #5209 | SPON 1

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

Ablation80%ACL Reconstruction80%Refractory Angina (this)67%Abuse, Drug60%Acceptability60%
Open-enrollment share among volume-matched conditions near Refractory Angina

Refractory Angina lists 2 open slots (67% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Refractory Angina on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Refractory Angina is recruiting above its size-band peers.

    2 of 3 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 21

Phase Distribution

PhaseTrial count
Phase 2 1

Top Sponsors

BioCardia 1 trials

Named interventions

Most-linked intervention names on Refractory Angina records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Sham Treatment Other
1 trials
CardiAMP Cell Therapy System Device
1 trials
Arm 3 (unblinded, non-randomized): Single arm registry Device
1 trials
Arm 2 (control): Implantation procedure with no device implanted Other
1 trials
Arm 1: treatment with Shockwave Reducer Device
1 trials
Sham (No Treatment) Combination
1 trials
XC001 Combination
1 trials

US sites by state

Facility locations filed on Refractory Angina trials. A trial with sites in several states counts in each.

Florida 2 trials
Wisconsin 1 trials
Ohio 1 trials
Georgia 1 trials
Connecticut 1 trials
Colorado 1 trials
California 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Refractory Angina page

3 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Refractory Angina trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Shockwave Medical sponsors the most Refractory Angina trials on record, review their full trial history before evaluating a specific study. See Shockwave Medical's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Refractory Angina condition card totals 3 registered trials; most-linked intervention Sham Treatment; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.