Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Pyruvate Dehydrogenase Complex Deficiency: full-pipeline trial registry
1 of 2 indexed Pyruvate Dehydrogenase Complex Deficiency trials are currently recruiting.
Corpus placement: #7,188 of 28,707 conditions by registered trial count.
2 US clinical trials · 1 currently recruiting · #7,188 of 28,707 conditions by registered trial count
Pyruvate Dehydrogenase Complex Deficiency: 2 US clinical trials tracked, 1 recruiting.
Pyruvate Dehydrogenase Complex Deficiency is the subject of 2 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Saol Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition pyruvate-dehydrogenase-complex-deficiency
OPEN 1 | RECR 50% | LATE 1 | EARLY 1 | RANK #7188 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Pyruvate Dehydrogenase Complex Deficiency lists 1 open slots (50% of 2 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pyruvate Dehydrogenase Complex Deficiency on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pyruvate Dehydrogenase Complex Deficiency is recruiting above its size-band peers.
1 of 2 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
2 total, page 1 of 1
Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency
Jirair Krikor Bedoyan
NCT06340685
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:
Saol Therapeutics
NCT02616484
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Pyruvate Dehydrogenase Complex Deficiency records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pyruvate Dehydrogenase Complex Deficiency trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pyruvate Dehydrogenase Complex Deficiency page
2 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 1 Pyruvate Dehydrogenase Complex Deficiency trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Saol Therapeutics sponsors the most Pyruvate Dehydrogenase Complex Deficiency trials on record, review their full trial history before evaluating a specific study. See Saol Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pyruvate Dehydrogenase Complex Deficiency condition card totals 2 registered trials; most-linked intervention Genotype; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.