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NCT05180162 · ClinicalTrials.gov registry record · Phase 1
Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286
A Phase 1 study of Pulmonary Fibrosis and Liver Fibrosis, sponsored by Thomas Hope.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT05180162 is a Phase 1 study of Pulmonary Fibrosis and Liver Fibrosis that has completed, run by Thomas Hope. The registered enrollment target is 16 participants, below the 888-participant average among 22 other Pulmonary Fibrosis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05180162, a Phase 1 study of Pulmonary Fibrosis and Liver Fibrosis, has completed, sponsored by Thomas Hope.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single arm prospective pilot trial that evaluates the ability of a novel imaging agent (68Ga-FAP-2286) to identify pathologic fibrosis in the setting of hepatic, cardiac and pulmonary fibrosis. FAP-2286 is a peptide that potently and selectively binds to Fibroblast Activation Protein (FAP). FAP is a transmembrane protein expressed on fibroblasts and has been shown to have higher expression in idiopathic pulmonary fibrosis (IPF), cirrhosis, and cardiac fibrosis.
Conditions Studied
Interventions
- DRUG 68Ga-FAP-2286
- PROCEDURE Positron Emission Tomography (PET)
Study Locations (1)
California
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2021-12-09 |
| Est. Completion | 2024-05-28 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05180162
The ClinicalTrials.gov registry entry for NCT05180162 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 888-participant average among 22 other Pulmonary Fibrosis trials with a reported enrollment target (98% lower). The listed sponsor is Thomas Hope, which has 13 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Pulmonary Fibrosis appearing as the primary indexed condition, and to 2 interventions - of which 68Ga-FAP-2286 is the first listed.
NCT05180162 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05180162 about?
NCT05180162 is a clinical study titled "Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286". This is a single arm prospective pilot trial that evaluates the ability of a novel imaging agent (68Ga-FAP-2286) to identify pathologic fibrosis in the setting of hepatic, cardiac and pulmonary fibrosis. FAP-2286 is a peptide that potently and selectively binds to Fibroblast Activation Protein (FAP...
What is the current status of trial NCT05180162?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2021-12-09. Estimated completion is 2024-05-28.
What conditions does trial NCT05180162 study?
This clinical trial studies the following conditions: Pulmonary Fibrosis, Liver Fibrosis, Myocardial Fibrosis.
What interventions are being tested in trial NCT05180162?
The interventions under investigation include: 68Ga-FAP-2286 (DRUG), Positron Emission Tomography (PET) (PROCEDURE).
Who is sponsoring clinical trial NCT05180162?
This trial is sponsored by Thomas Hope, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05180162 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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