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Pre Diabetes clinical trials
22 of 60 indexed Pre Diabetes trials are currently recruiting.
60 US clinical trials · 22 currently recruiting
Pre Diabetes is the subject of 60 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Clinical Nutrition Research Center, Illinois Institute of Technology, running 4 of these trials.
The research picture
Pre Diabetes has 60 registered US clinical trials, 22 of them open to new participants right now, about 37% of the total.
- 22
- recruiting participants now
- 37%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology
Active & Recent Trials
60 total, page 2 of 2
Diabetes Prevention Program Pilot
Penn State University
NCT04651816
Time Restricted Eating on Cancer Risk
Medical University of South Carolina
NCT05038137
Continuous Glucose Monitoring in Prediabetes
University of Southern California
NCT06472297
Incretins in Impaired Fasting Glucose
Mayo Clinic
NCT00364377
A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes
Novartis
NCT00312130
The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion
Washington University School of Medicine
NCT01951729
Continuous Glucose Monitoring (CGM) With a Low Carbohydrate Diet to Reduce Weight in Patients With Pre-Diabetes
University of Michigan
NCT03695913
Effect of Food Order on Postprandial Glucose Excursions in Pre-Diabetes
Weill Medical College of Cornell University
NCT03536364
Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time
Arizona State University
NCT04144920
Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness
Katherine Vickery
NCT06025721
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Pre Diabetes Trial Landscape
60 indexed Pre Diabetes studies · 22 recruiting (37%).
Phase mix: 4 late (III/IV) vs 4 early (I/II).
Top sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology (4 trials), 9 others listed. 10 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Pre Diabetes?
PlainTrial tracks 60 US clinical trials for Pre Diabetes, of which 22 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Pre Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.