Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Painful Diabetic Neuropathy: early-phase trial registry
3 of 6 indexed Painful Diabetic Neuropathy trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Painful Diabetic Neuropathy: 6 US clinical trials tracked, 3 recruiting.
Painful Diabetic Neuropathy is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Arcion Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition painful-diabetic-neuropathy
OPEN 3 | RECR 50% | LATE 0 | EARLY 3 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
Painful Diabetic Neuropathy lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Painful Diabetic Neuropathy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Painful Diabetic Neuropathy is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Painful Diabetic Neuropathy research.
Arcion Therapeutics accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
-
Typical Painful Diabetic Neuropathy enrolment sits around 143 participants.
Median target enrolment is 143 among the 6 trials that report a genuine target (sentinel values excluded). 2 of those (33.3%) plan for fewer than 100 participants.
-
Painful Diabetic Neuropathy research is mostly interventional.
5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral Neuropathy
Averitas Pharma
NCT06495424
Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy
Dartmouth-Hitchcock Medical Center
NCT04678895
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
University of Nebraska
NCT06480786
Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic Neuropathy
Nevro
NCT05777317
Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy
Arcion Therapeutics
NCT00695565
The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy
BioDelivery Sciences International
NCT02643251
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Painful Diabetic Neuropathy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Painful Diabetic Neuropathy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Painful Diabetic Neuropathy page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Painful Diabetic Neuropathy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Arcion Therapeutics sponsors the most Painful Diabetic Neuropathy trials on record, review their full trial history before evaluating a specific study. See Arcion Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Painful Diabetic Neuropathy condition card totals 6 registered trials; most-linked intervention Clonidine Hydrochloride Gel Comparator; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.