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Painful Diabetic Neuropathy clinical trials
3 of 6 indexed Painful Diabetic Neuropathy trials are currently recruiting.
6 US clinical trials · 3 currently recruiting
Painful Diabetic Neuropathy is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Arcion Therapeutics, running 1 of these trials.
The research picture
Painful Diabetic Neuropathy has 6 registered US clinical trials, 3 of them open to new participants right now, about 50% of the total.
- 3
- recruiting participants now
- 50%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Arcion Therapeutics
Active & Recent Trials
6 total, page 1 of 1
Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral Neuropathy
Averitas Pharma
NCT06495424
Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy
Dartmouth-Hitchcock Medical Center
NCT04678895
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
University of Nebraska
NCT06480786
Pain and Neurological Function Improvements With 10 kHz Spinal Cord Stimulation Treatment of Painful Diabetic Neuropathy
Nevro
NCT05777317
Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy
Arcion Therapeutics
NCT00695565
The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy
BioDelivery Sciences International
NCT02643251
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Painful Diabetic Neuropathy Trial Landscape
6 indexed Painful Diabetic Neuropathy studies · 3 recruiting (50%).
Phase mix: 0 late (III/IV) vs 3 early (I/II).
Top sponsor: Arcion Therapeutics (1 trial), 5 others listed. 6 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Painful Diabetic Neuropathy?
PlainTrial tracks 6 US clinical trials for Painful Diabetic Neuropathy, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Painful Diabetic Neuropathy?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.