Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Oral Cancer: early-phase trial registry
9 of 18 indexed Oral Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #953 of 28,707 conditions by registered trial count.
18 US clinical trials · 9 currently recruiting · #953 of 28,707 conditions by registered trial count
Oral Cancer: 18 US clinical trials tracked, 9 recruiting.
Oral Cancer is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is UNC Lineberger Comprehensive Cancer Center, running 2 of these trials.
Enrollment posture brief
Registry condition oral-cancer
OPEN 9 | RECR 50% | LATE 0 | EARLY 6 | RANK #953 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Oral Cancer lists 9 open slots (50% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Oral Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Oral Cancer is recruiting above its size-band peers.
9 of 18 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Oral Cancer trials is spread across many organizations.
UNC Lineberger Comprehensive Cancer Center accounts for 2 of 18 trials (11.1%). 16 distinct sponsors appear on at least one study for this condition label.
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Most Oral Cancer trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 18 trials that report a genuine target (sentinel values excluded). 13 of those (72.2%) plan for fewer than 100 participants.
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Oral Cancer research is mostly interventional.
14 interventional and 4 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
18 total, page 1 of 1
Clinical and Molecular Features of Oral Premalignancy and Oral Cancer
M.D. Anderson Cancer Center
NCT06550050
Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Controlled Trial
Tobias Todsen
NCT07203911
Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain
New York University
NCT07095608
Microbiome in Head and Neck Squamous Cell Carcinoma
University of Colorado, Denver
NCT05837221
Enhancing Oral Cancer Awareness
Virginia Commonwealth University
NCT06682494
Defining Mechanisms of Surgical Site Infection After Oral Cancer Surgery
Medical College of Wisconsin
NCT06681935
Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue
University of Michigan
NCT02584270
Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction
Case Comprehensive Cancer Center
NCT07110142
Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer
Case Comprehensive Cancer Center
NCT06627270
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial
Rutgers, The State University of New Jersey
NCT04713449
Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer
Loren Mell, MD
NCT03383094
Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma
UNC Lineberger Comprehensive Cancer Center
NCT03174275
The Use of Functional Confections in Promoting Oral Health
Ohio State University
NCT01514552
Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN
UNC Lineberger Comprehensive Cancer Center
NCT03529422
Evaluations of Alcohol Warning Labels
University of Connecticut
NCT06129487
A Study of the Effects of PEITC on Oral Cells With Mutant p53
Georgetown University
NCT01790204
Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization Phase
Duke University
NCT04905134
Cigarette Smoking and Oral Microbiota
National Cancer Institute (NCI)
NCT01862809
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Oral Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Oral Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Oral Cancer page
18 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Oral Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- UNC Lineberger Comprehensive Cancer Center sponsors the most Oral Cancer trials on record, review their full trial history before evaluating a specific study. See UNC Lineberger Comprehensive Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Oral Cancer condition card totals 18 registered trials; most-linked intervention Durvalumab; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.