Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 29 recruiting now official registry

Non-small Cell Lung Cancer (NSCLC) clinical trials

29 of 59 indexed Non-small Cell Lung Cancer (NSCLC) trials are currently recruiting.

59 US clinical trials · 29 currently recruiting

Non-small Cell Lung Cancer (NSCLC) is the subject of 59 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 47 in Phase 1-2 (earlier-stage). The most active sponsor is Revolution Medicines, running 7 of these trials.

The research picture

Non-small Cell Lung Cancer (NSCLC) has 59 registered US clinical trials, 29 of them open to new participants right now, about 49% of the total.

29
recruiting participants now
49%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
7
top sponsor: Revolution Medicines
Phase 136Phase 211Phase 38Phase 41

Active & Recent Trials

59 total, page 2 of 2

COMPLETED Phase 2 47 participants

A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients

Academic Thoracic Oncology Medical Investigators Consortium

NCT02879617

COMPLETED NA 30 participants

FDG PET/CT in Lung Cancer Staging

Abramson Cancer Center at Penn Medicine

NCT02738398

COMPLETED Phase 1 26 participants

Bavituximab Plus Carbo and Pemetrexed in Chemo-Naive Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Subjects

UNC Lineberger Comprehensive Cancer Center

NCT01323062

COMPLETED Phase 1 24 participants

A Trial of CV301 in Combination With Anti-PD-1 Therapy in Subjects With Non-Small Cell Lung Cancer

Bavarian Nordic

NCT02840994

COMPLETED Phase 1 23 participants

Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors

University of California, Davis

NCT01336842

COMPLETED Phase 1 17 participants

Vorinostat in Combination With Palliative Radiotherapy for Patients With Non-Small Cell Lung Cancer

Yale University

NCT00821951

COMPLETED Phase 1 14 participants

Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer

Syndax Pharmaceuticals

NCT01594398

COMPLETED Phase 2 8 participants

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration

Incyte Corporation

NCT05253807

COMPLETED Phase 1 5 participants

Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer

Concordia Laboratories

NCT02916745

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 36
Phase 2 11
Phase 3 8
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Non-small Cell Lung Cancer (NSCLC) Trial Landscape

59 indexed Non-small Cell Lung Cancer (NSCLC) studies · 29 recruiting (49%).

Phase mix: 9 late (III/IV) vs 47 early (I/II).

Top sponsor: Revolution Medicines (7 trials), 9 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Non-small Cell Lung Cancer (NSCLC)?

PlainTrial tracks 59 US clinical trials for Non-small Cell Lung Cancer (NSCLC), of which 29 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Non-small Cell Lung Cancer (NSCLC)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.