Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Nicotine Pouch Self-Administration: early-phase trial registry
2 of 3 indexed Nicotine Pouch Self-Administration trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #5,209 of 28,707 conditions by registered trial count.
3 US clinical trials · 2 currently recruiting · #5,209 of 28,707 conditions by registered trial count
Nicotine Pouch Self-Administration: 3 US clinical trials tracked, 2 recruiting.
Nicotine Pouch Self-Administration is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is William Middleton, running 1 of these trials.
Enrollment posture brief
Registry condition nicotine-pouch-self-administration
OPEN 2 | RECR 67% | LATE 0 | EARLY 1 | RANK #5209 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)
Nicotine Pouch Self-Administration lists 2 open slots (67% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Nicotine Pouch Self-Administration on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Nicotine Pouch Self-Administration is recruiting above its size-band peers.
2 of 3 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
3 total, page 1 of 1
Acute Effects of Oral Nicotine Pouches
Johns Hopkins University
NCT07128329
Effects of Nicotine Pouch Characteristics on Perceptions and Behavior
University of Southern California
NCT06597435
Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage
William Middleton
NCT07213947
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Nicotine Pouch Self-Administration records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Nicotine Pouch Self-Administration trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Nicotine Pouch Self-Administration page
3 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Nicotine Pouch Self-Administration trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- William Middleton sponsors the most Nicotine Pouch Self-Administration trials on record, review their full trial history before evaluating a specific study. See William Middleton's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Nicotine Pouch Self-Administration condition card totals 3 registered trials; most-linked intervention Nicotine Pouch Dosage; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.