Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov enrollment closed early-phase tilt small index

Metastatic Urethral Urothelial Carcinoma: early-phase trial registry

A small indexed set (8 trials) with no open enrollment listed right now.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · none currently recruiting · #2,176 of 28,707 conditions by registered trial count

Metastatic Urethral Urothelial Carcinoma: 8 US clinical trials tracked, none currently recruiting.

Metastatic Urethral Urothelial Carcinoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 4 of these trials.

Enrollment posture brief

Registry condition metastatic-urethral-urothelial-carcinoma

OPEN 0 | RECR 0% | LATE 2 | EARLY 6 | RANK #2176 | SPON 4

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)

Activity, Motor75%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%Metastatic Urethral Urot (th…0%
Open-enrollment share among volume-matched conditions near Metastatic Urethral Urothelial Carcinoma

Metastatic Urethral Urothelial Carcinoma has no open enrollment in this registry pull (8 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Urethral Urothelial Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Urethral Urothelial Carcinoma is recruiting below its size-band peers.

    0 of 8 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Urethral Urothelial Carcinoma research.

    National Cancer Institute (NCI) accounts for 4 of 8 trials (50%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Urethral Urothelial Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 24 among the 8 trials that report a genuine target (sentinel values excluded). 7 of those (87.5%) plan for fewer than 100 participants.

  4. Metastatic Urethral Urothelial Carcinoma research is mostly interventional.

    8 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 24Phase 32

Indexed trials (enrollment closed)

8 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3 654 participants

Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study

National Cancer Institute (NCI)

NCT05092958

ACTIVE NOT RECRUITING Phase 2 72 participants

Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer

National Cancer Institute (NCI)

NCT03237780

ACTIVE NOT RECRUITING Phase 1 24 participants

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

National Cancer Institute (NCI)

NCT04963153

ACTIVE NOT RECRUITING Phase 1 15 participants

Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate

Jonsson Comprehensive Cancer Center

NCT03582475

ACTIVE NOT RECRUITING Phase 2 6 participants

ARID1A and/or KDM6A Mutation and CXCL13 Expression

M.D. Anderson Cancer Center

NCT04953104

ACTIVE NOT RECRUITING Phase 2 6 participants

Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma

Emory University

NCT04848519

ACTIVE NOT RECRUITING Phase 3 3 participants

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

Alliance for Clinical Trials in Oncology

NCT04637594

COMPLETED Phase 2 47 participants

Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma

National Cancer Institute (NCI)

NCT03513952

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 2

Named interventions

Most-linked intervention names on Metastatic Urethral Urothelial Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
4 trials
Avelumab Drug
3 trials
Atezolizumab Drug
3 trials
Computed Tomography Procedure
3 trials
Nivolumab Drug
2 trials
Bone Scan Procedure
2 trials
Pembrolizumab Drug
2 trials
Glycosylated Recombinant Human Interleukin-7 Biological
1 trials

US sites by state

Facility locations filed on Metastatic Urethral Urothelial Carcinoma trials. A trial with sites in several states counts in each.

California 6 trials
Florida 3 trials
Texas 2 trials
New York 2 trials
Missouri 2 trials
Arizona 2 trials
Washington 1 trials
Utah 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Urethral Urothelial Carcinoma page

8 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • No Metastatic Urethral Urothelial Carcinoma trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • National Cancer Institute (NCI) sponsors the most Metastatic Urethral Urothelial Carcinoma trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Urethral Urothelial Carcinoma condition card totals 8 registered trials; most-linked intervention Biospecimen Collection; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.