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ClinicalTrials.gov 4 recruiting now official registry

Metastatic Laryngeal Squamous Cell Carcinoma clinical trials

4 of 8 indexed Metastatic Laryngeal Squamous Cell Carcinoma trials are currently recruiting.

8 US clinical trials · 4 currently recruiting

Metastatic Laryngeal Squamous Cell Carcinoma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Emory University, running 3 of these trials.

The research picture

Metastatic Laryngeal Squamous Cell Carcinoma has 8 registered US clinical trials, 4 of them open to new participants right now, about 50% of the total.

4
recruiting participants now
50%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
3
top sponsor: Emory University
Phase 11Phase 24Phase 32

Active & Recent Trials

8 total, page 1 of 1

RECRUITING Phase 3 158 participants

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

National Cancer Institute (NCI)

NCT06589804

RECRUITING NA 118 participants

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Emory University

NCT06662058

RECRUITING Phase 1 40 participants

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Emory University

NCT06868433

RECRUITING Phase 2 28 participants

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Emory University

NCT06636734

ACTIVE NOT RECRUITING Phase 2 430 participants

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

National Cancer Institute (NCI)

NCT05063552

ACTIVE NOT RECRUITING Phase 3 290 participants

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

ECOG-ACRIN Cancer Research Group

NCT05721755

ACTIVE NOT RECRUITING Phase 2 52 participants

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

National Cancer Institute (NCI)

NCT05172258

ACTIVE NOT RECRUITING Phase 2 46 participants

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Marcelo Bonomi

NCT04862650

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastatic Laryngeal Squamous Cell Carcinoma Trial Landscape

8 indexed Metastatic Laryngeal Squamous Cell Carcinoma studies · 4 recruiting (50%).

Phase mix: 2 late (III/IV) vs 5 early (I/II).

Top sponsor: Emory University (3 trials), 3 others listed. 8 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastatic Laryngeal Squamous Cell Carcinoma?

PlainTrial tracks 8 US clinical trials for Metastatic Laryngeal Squamous Cell Carcinoma, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastatic Laryngeal Squamous Cell Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.