Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
HFrEF - Heart Failure With Reduced Ejection Fraction: early-phase trial registry
2 of 2 indexed HFrEF - Heart Failure With Reduced Ejection Fraction trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #7,188 of 28,707 conditions by registered trial count.
2 US clinical trials · 2 currently recruiting · #7,188 of 28,707 conditions by registered trial count
HFrEF - Heart Failure With Reduced Ejection Fraction: 2 US clinical trials tracked, 2 recruiting.
HFrEF - Heart Failure With Reduced Ejection Fraction is the subject of 2 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Sardocor, running 1 of these trials.
Enrollment posture brief
Registry condition hfref-heart-failure-with-reduced-ejection-fraction
OPEN 2 | RECR 100% | LATE 0 | EARLY 2 | RANK #7188 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
HFrEF - Heart Failure With Reduced Ejection Fraction lists 2 open slots (100% of 2 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for HFrEF - Heart Failure With Reduced Ejection Fraction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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HFrEF - Heart Failure With Reduced Ejection Fraction is recruiting above its size-band peers.
2 of 2 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
2 total, page 1 of 1
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor
NCT04703842
Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension
Salubris Biotherapeutics
NCT07221513
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on HFrEF - Heart Failure With Reduced Ejection Fraction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on HFrEF - Heart Failure With Reduced Ejection Fraction trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this HFrEF - Heart Failure With Reduced Ejection Fraction page
2 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 HFrEF - Heart Failure With Reduced Ejection Fraction trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Sardocor sponsors the most HFrEF - Heart Failure With Reduced Ejection Fraction trials on record, review their full trial history before evaluating a specific study. See Sardocor's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This HFrEF - Heart Failure With Reduced Ejection Fraction condition card totals 2 registered trials; most-linked intervention SRD-001; top US site state Washington. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.