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E-Cig Use clinical trials
6 of 10 indexed E-Cig Use trials are currently recruiting.
10 US clinical trials · 6 currently recruiting
E-Cig Use is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 2 of these trials.
The research picture
E-Cig Use has 10 registered US clinical trials, 6 of them open to new participants right now, about 60% of the total.
- 6
- recruiting participants now
- 60%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Virginia Commonwealth University
Active & Recent Trials
10 total, page 1 of 1
The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers
Abramson Cancer Center at Penn Medicine
NCT06264154
Clinical Alternatives for Reducing Harm Using E-cigarettes
Medical University of South Carolina
NCT07039292
Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)
Roswell Park Cancer Institute
NCT07167225
BREATHE Free: a Pilot Feasibility Trial
Augusta University
NCT06862050
The Impact of Chronic E-Cigarette Usage on Microvascular Health
Virginia Commonwealth University
NCT06860698
Hyperpolarized Xenon-129 MR Imaging of the Lung
University of Virginia
NCT04662658
Respiratory Effects of E-Cigarettes in Obese Youth
Ohio State University Comprehensive Cancer Center
NCT05869318
Quit Smoking Study for People Who Use E-Cigarettes
University of Vermont
NCT04946825
Media Literacy for High School Tobacco Prevention
University of Pittsburgh
NCT05120466
The Acute Effect of Vaping on Food Intake
Virginia Commonwealth University
NCT04219189
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the E-Cig Use Trial Landscape
10 indexed E-Cig Use studies · 6 recruiting (60%).
Phase mix: 0 late (III/IV) vs 2 early (I/II).
Top sponsor: Virginia Commonwealth University (2 trials), 8 others listed. 10 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for E-Cig Use?
PlainTrial tracks 10 US clinical trials for E-Cig Use, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for E-Cig Use?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.