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Covid19 clinical trials
12 of 95 indexed Covid19 trials are currently recruiting.
95 US clinical trials · 12 currently recruiting
Covid19 is the subject of 95 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 4 of these trials.
The research picture
Covid19 has 95 registered US clinical trials, 12 of them open to new participants right now, about 13% of the total.
- 12
- recruiting participants now
- 13%
- of trials open to enrollment
- 12
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
95 total, page 2 of 2
Asymptomatic SARS-CoV-2 Detection in Children
University of Calgary
NCT04853316
Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19
Vir Biotechnology
NCT04779879
A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
Lucira Health
NCT04720235
A Retrospective Study of COVID-19 Treatments
ProgenaBiome
NCT04949230
Evaluation of the INDICAID™ COVID-19 Rapid Antigen Test
University of California, Los Angeles
NCT04904510
Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
New York Hospital Queens
NCT05130541
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)
BeiGene
NCT04551898
Post COVID-19 Vaccination Analysis in Healthcare Worker Recipients
Huntington Memorial Hospital
NCT04922944
Northern Colorado COVID-19 Biobank
Colorado State University
NCT04603677
Covid-19 Vaccine Responsiveness in MM and Waldenstrom
Massachusetts General Hospital
NCT04830046
Impact of Colchicine and Low-dose Naltrexone on COVID-19
HealthPartners Institute
NCT04756128
Clinical Evaluation of a Point-of-Care (POC), COVID-19 Rapid Antigen Test (CoviDx™)
Lumos Diagnostics
NCT04750629
COVID-19 Project ECHO in Nursing Homes
Milton S. Hershey Medical Center
NCT04499391
Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
University of Oklahoma
NCT04707534
KBP-201 COVID-19 Vaccine Trial in Healthy Volunteers
KBio
NCT04473690
A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther Fusion
Lucira Health
NCT04720794
Aggrenox To Treat Acute Covid-19
Rutgers, The State University of New Jersey
NCT04410328
Evaluate Long Term Cardiovascular and Pulmonary Complications After COVID-19 With Point of Care Ultrasound
University of Louisville
NCT04756193
Augmentation of Immune Response to COVID-19 mRNA Vaccination Through OMT With Lymphatic Pumps
Western University of Health Sciences
NCT04928456
Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06729593
Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19
University of Michigan
NCT05200819
RCT of Modified Qing Fei Pai Du Tang (mQFPD) for COVID-19
University of California, San Diego
NCT04939415
COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications
James L. Kirkland, MD, PhD
NCT04771611
Baseline Vitamin D Deficiency and COVID-19 Disease Severity
Parkview Medical Center
NCT04628000
Nebulized Heparin for the Treatment of COVID-19
Frederick Health
NCT04723563
Breath Analysis Based Disease Biomarkers
Mayo Clinic
NCT04341012
REgulatory T Cell infuSion fOr Lung Injury Due to COVID-19 PnEumonia
Cellenkos
NCT04468971
Clinical Validation of New Injection Molded Flocked Nasopharyngeal Swabs in Response to the COVID-19 Pandemic
University of Virginia
NCT04368260
Blood Volume Assessment in COVID-19 and Bacterial Sepsis
NYU Langone Health
NCT04517695
Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults and Boost (VXA-CoV2-1.1-S) at 1 Year Post Initial Vaccination in Subset of Subjects
Vaxart
NCT04563702
Transfer of Infection Fighting Immune Cells Generated in the Laboratory to High Risk Patients With COVID-19 Infection
Thomas Jefferson University
NCT04765449
DCI COVID-19 Surveillance Project
Temple University
NCT04780698
Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients
Cytokind
NCT04818970
Prognostic Models for COVID-19 Care
Tufts Medical Center
NCT04689711
Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19
Senhwa Biosciences
NCT04663737
Core Warming in COVID-19 Patients Undergoing Mechanical Ventilation
Sharp HealthCare
NCT04494867
A Trial of Aclaris Therapeutics, Inc. (ATI)-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19)
University of Kansas Medical Center
NCT04481685
Electrical Stimulation for Critically Ill Covid-19 Patients
Baylor College of Medicine
NCT04685213
Performance of a Remote Monitoring Program for Patients Diagnosed With COVID-19
George Washington University
NCT05063812
COVID-19 Study of Safety and Tolerability of Alvelestat
University of Alabama at Birmingham
NCT04539795
Cardiovascular, Pulmonary, and Integrative Functional Phenotypes in COVID-19 Survivors - Effect of Fenofibrate
University of Pennsylvania
NCT05080192
Prognostication of Recovery in Early Disorders of Consciousness After COVID-19
Massachusetts General Hospital
NCT04476589
Implementation of COVID-19 Testing Strategies in Community Health Centers
Massachusetts General Hospital
NCT04802187
Contrast Enhanced Ultrasound in COVID-19
Children's Hospital of Philadelphia
NCT04640038
Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19
Memorial Sloan Kettering Cancer Center
NCT04824443
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 13 |
| Phase 3 | 10 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Covid19 Trial Landscape
95 indexed Covid19 studies · 12 recruiting (13%).
Phase mix: 12 late (III/IV) vs 23 early (I/II).
Top sponsor: Massachusetts General Hospital (4 trials), 9 others listed. 45 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Covid19?
PlainTrial tracks 95 US clinical trials for Covid19, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Covid19?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.