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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)
NCT04551898 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to evaluate the efficacy of BGB-DXP593 administered intravenously as a single dose in participants with mild to moderate COVID-19
Conditions Studied
Interventions
- DRUG Placebo
- DRUG BGB-DXP593
Study Locations (18)
Florida
- Btc Network Midland Florida Clinical Research Center — DeLand
- Elixia Clinical Research Collaborative — Hollywood
- Homestead Associates in Research Inc — Miami
- Medical Research Center of Miami Ii, Inc — Miami
- Us Associates in Research — Miami
- Continental Research Network — Miami
- Orlando Health Ufhealth Cancer Center — Orlando
Other
- Hospital Das Clinicas Da Faculdade de Medicina de Botucatu — Botucatu
- Fundacao Universidade de Caxias Do Sul — Caxias do Sul
- Consultoria Medica E Pesquisa Clinica — Sorcaba
- Hospital Cardiologica Aguascalientes — Aguascalientes
- IECSI — Monterrey
- Task Clinical Research Centre — Cape Town
- Langeberg Clinical Trials — Cape Town
Michigan
- Revive Research Institute — Dearborn
- Revival Research Institute Farmington Hills — Sterling Heights
Texas
- Amarillo Center For Clinical Research — Amarillo
- Panamerican Clinical Research Us Headquarters — Brownsville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 181 participants |
| Start Date | 2020-12-02 |
| Est. Completion | 2021-05-25 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04551898
The ClinicalTrials.gov registry entry for NCT04551898 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 181 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BeiGene, which has 91 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Covid19 appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04551898 reports 18 study locations spanning 4 distinct geographic areas — top geographies include Florida, Other, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04551898 about?
NCT04551898 is a clinical study titled "Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)". The primary objective of this study is to evaluate the efficacy of BGB-DXP593 administered intravenously as a single dose in participants with mild to moderate COVID-19
What is the current status of trial NCT04551898?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 181 participants. The study started on 2020-12-02. Estimated completion is 2021-05-25.
What conditions does trial NCT04551898 study?
This clinical trial studies the following conditions: Covid19. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04551898?
The interventions under investigation include: Placebo (DRUG), BGB-DXP593 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04551898?
This trial is sponsored by BeiGene, which has 91 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04551898 being conducted?
This trial has 18 study locations across Florida, Michigan, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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