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COMPLETED Phase 2

Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19

NCT04779879 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase 2 study in which subjects with coronavirus disease 2019 (COVID-19) will receive VIR-7831 (Sotrovimab) Generation 1 (Gen1) or VIR-7831 (Sotrovimab) Generation 2 (Gen2) and will be assessed for safety, tolerability, and pharmacokinetics.

Conditions Studied

Interventions

  • BIOLOGICAL Sotrovimab (Gen1)
  • BIOLOGICAL Sotrovimab (Gen2)

Study Locations (20)

Florida

  • Investigative Site — Ft. Pierce
  • Investigative Site — Gainesville
  • Investigative Site — Hialeah
  • Investigative Site — Miami
  • Investigative Site — Miami
  • Investigative Site — Miami
  • Investigative Site — Miami
  • Investigative Site — Orlando
  • Investigative Site — Pembroke Pines
  • Investigative Site — Tampa

California

  • Investigative Site — Bakersfield
  • Investigative Site — Northridge

Ontario

  • Investigative Site — Sarnia
  • Investigative Site — Toronto

Alabama

  • Investigative Site — Anniston

Georgia

  • Investigative Site — Columbus

Illinois

  • Investigative Site — Winfield

Maryland

  • Investigative Site — Rockville

New York

  • Investigative Site — The Bronx

Trial Details

FieldValue
Enrollment Target 354 participants
Start Date 2021-02-18
Est. Completion 2022-04-06
Phase Phase 2

Sponsor

Vir Biotechnology

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04779879

The ClinicalTrials.gov registry entry for NCT04779879 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 354 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vir Biotechnology, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Covid19 appearing as the primary indexed condition, and to 2 interventions — of which Sotrovimab (Gen1) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04779879 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Ontario. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04779879 about?

NCT04779879 is a clinical study titled "Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19". This is a phase 2 study in which subjects with coronavirus disease 2019 (COVID-19) will receive VIR-7831 (Sotrovimab) Generation 1 (Gen1) or VIR-7831 (Sotrovimab) Generation 2 (Gen2) and will be assessed for safety, tolerability, and pharmacokinetics.

What is the current status of trial NCT04779879?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 354 participants. The study started on 2021-02-18. Estimated completion is 2022-04-06.

What conditions does trial NCT04779879 study?

This clinical trial studies the following conditions: Covid19. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04779879?

The interventions under investigation include: Sotrovimab (Gen1) (BIOLOGICAL), Sotrovimab (Gen2) (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04779879?

This trial is sponsored by Vir Biotechnology, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04779879 being conducted?

This trial has 20 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial