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Covid19
Open-data reference.
90 US clinical trials · 11 currently recruiting
Active & Recent Trials
COVID-19 Risk Assessment for Hospitalization Outcomes and Epidemiology Efficacy
Aventyn
NCT04678193
Conversations You Want About Corona Virus Disease (COVID-19)
Wake Forest University Health Sciences
NCT05191420
COVID-19 Vaccines International Pregnancy Exposure Registry
Pregistry
NCT04705116
COVID-19 International Drug Pregnancy Registry
Pregistry
NCT05013632
KIDney Injury in Times of COVID-19 (KIDCOV)
University of California, San Francis
NCT04705766
COVID-19 Survivorship Registry
NYU Langone Health
NCT04527315
Outpatient Treatment With Anti-Coronavirus Immunoglobulin
University of Minnesota
NCT04910269
A Multimodal Parent-focused Intervention for Vulnerable Populations in the Bronx
Albert Einstein College of Medicine
NCT04991467
Imaging Immune Activation in COVID-19
CellSight Technologies
NCT04815096
Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure
Jon Simmons
NCT04445285
Defibrotide for the Treatment of Severe COVID-19
Brigham and Women's Hospital
NCT04652115
Pediatric COVID Outcomes Study (PECOS)
Children's National Research Institute
NCT04830852
Improving Health Equity for COVID-19 Vaccination for At-risk Populations Using Online Social Networks
University of Pennsylvania
NCT04779827
Risk Stratification of COVID-19 Using Urine Biomarkers
National Center for Global Health and Medicine, Japan
NCT04681040
Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs
NDRI-USA
NCT04924803
Post Acute Sequelae of COVID-19
Vanderbilt University Medical Center
NCT04964115
SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial
Milton S. Hershey Medical Center
NCT04802408
Repeat BCG Vaccinations for the Treatment of Established Type 1 Diabetes
Massachusetts General Hospital
NCT02081326
COVID-FISETIN: Pilot in SARS-CoV-2 of Fisetin to Alleviate Dysfunction and Inflammation
Mayo Clinic
NCT04476953
High Resolution Micro OCT Imaging
University of Alabama at Birmingham
NCT03256773
A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults
Restorbio
NCT04584710
REsearching Covid-19 Outcomes in Diabetes (RECODE)
AdventHealth Translational Research Institute
NCT04805970
Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair
NCT03305341
Hyperpolarized 129Xe MRI of Survivors of COVID-19
University of Kansas Medical Center
NCT04659707
COVID-19 Citizen Science Expansion Project
University of California, San Francis
NCT05548803
A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2
Novavax
NCT04611802
Communities Fighting COVID-19!
San Diego State University
NCT05148936
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
Beth Israel Deaconess Medical Center
NCT04498442
Test to Stay in School: COVID-19 Testing Following Exposure in School Communities
Duke University
NCT05052580
Use of Construal Level Theory to Inform Messaging to Increase Vaccination Against COVID-19
Brigham and Women's Hospital
NCT04871776
Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19
University of Michigan
NCT04706533
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)
Susanna Naggie, MD
NCT06042855
Real World Study of COVID-19 in a Flyover Region
Tulane University
NCT04962347
A Smartphone Intervention for Relational and Mental Well Being
University of Washington
NCT04629755
Equitable Access to COVID-19 Vaccines
Mayo Clinic
NCT04952376
COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)
University of Minnesota
NCT04510194
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm E (Fluvoxamine 100)
Susanna Naggie, MD
NCT05894564
Social Activity, Loneliness and Stigma During COVID-19 Outbreak
Columbia University
NCT04734171
Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic
Washington University School of Medicine
NCT04565509
Vitamin D3 Supplementation to Prevent Respiratory Tract Infections
The Cooper Health System
NCT04596657
The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign
National Bureau of Economic Research
NCT04644328
Views on COVID-19 and Vaccination
University of Massachusetts, Worcester
NCT04706403
Prophylactic Versus Therapeutic Dose Anticoagulation In COVID-19 Infection at the Time of Admission To Critical Care Units
Corewell Health East
NCT04829552
Minnesota COVID-19 Testing Project
Harvard University
NCT04568889
Convalescent Plasma in Outpatients With COVID-19
Stanford University
NCT04355767
COVID-19 IgG Formation in Physicians at ALGH and Their Household Members
Wake Forest University Health Sciences
NCT04540484
COVID-19 SAFE Enrollment
University of Pennsylvania
NCT04506268
Lung Ultrasound Implementation in the Management of Patients Hospitalized With COVID-19
University of Colorado, Denver
NCT04542421
Asymptomatic SARS-CoV-2 Detection in Children
University of Calgary
NCT04853316
Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19
Vir Biotechnology
NCT04779879
A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
Lucira Health
NCT04720235
A Retrospective Study of COVID-19 Treatments
ProgenaBiome
NCT04949230
Evaluation of the INDICAID™ COVID-19 Rapid Antigen Test
University of California, Los Angeles
NCT04904510
Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
New York Hospital Queens
NCT05130541
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)
BeiGene
NCT04551898
Post COVID-19 Vaccination Analysis in Healthcare Worker Recipients
Huntington Memorial Hospital
NCT04922944
Northern Colorado COVID-19 Biobank
Colorado State University
NCT04603677
Covid-19 Vaccine Responsiveness in MM and Waldenstrom
Massachusetts General Hospital
NCT04830046
Impact of Colchicine and Low-dose Naltrexone on COVID-19
HealthPartners Institute
NCT04756128
Clinical Evaluation of a Point-of-Care (POC), COVID-19 Rapid Antigen Test (CoviDx™)
Lumos Diagnostics
NCT04750629
COVID-19 Project ECHO in Nursing Homes
Milton S. Hershey Medical Center
NCT04499391
Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
University of Oklahoma
NCT04707534
KBP-201 COVID-19 Vaccine Trial in Healthy Volunteers
KBio
NCT04473690
A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther Fusion
Lucira Health
NCT04720794
Aggrenox To Treat Acute Covid-19
Rutgers, The State University of New Jersey
NCT04410328
Evaluate Long Term Cardiovascular and Pulmonary Complications After COVID-19 With Point of Care Ultrasound
University of Louisville
NCT04756193
Augmentation of Immune Response to COVID-19 mRNA Vaccination Through OMT With Lymphatic Pumps
Western University of Health Sciences
NCT04928456
Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06729593
Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19
University of Michigan
NCT05200819
RCT of Modified Qing Fei Pai Du Tang (mQFPD) for COVID-19
University of California, San Diego
NCT04939415
COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications
James L. Kirkland, MD, PhD
NCT04771611
Baseline Vitamin D Deficiency and COVID-19 Disease Severity
Parkview Medical Center
NCT04628000
Nebulized Heparin for the Treatment of COVID-19
Frederick Health
NCT04723563
Blood Volume Assessment in COVID-19 and Bacterial Sepsis
NYU Langone Health
NCT04517695
Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults and Boost (VXA-CoV2-1.1-S) at 1 Year Post Initial Vaccination in Subset of Subjects
Vaxart
NCT04563702
Transfer of Infection Fighting Immune Cells Generated in the Laboratory to High Risk Patients With COVID-19 Infection
Thomas Jefferson University
NCT04765449
DCI COVID-19 Surveillance Project
Temple University
NCT04780698
Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients
Cytokind
NCT04818970
Prognostic Models for COVID-19 Care
Tufts Medical Center
NCT04689711
Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19
Senhwa Biosciences
NCT04663737
Core Warming in COVID-19 Patients Undergoing Mechanical Ventilation
Sharp HealthCare
NCT04494867
A Trial of Aclaris Therapeutics, Inc. (ATI)-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19)
University of Kansas Medical Center
NCT04481685
Electrical Stimulation for Critically Ill Covid-19 Patients
Baylor College of Medicine
NCT04685213
Performance of a Remote Monitoring Program for Patients Diagnosed With COVID-19
George Washington University
NCT05063812
COVID-19 Study of Safety and Tolerability of Alvelestat
University of Alabama at Birmingham
NCT04539795
Cardiovascular, Pulmonary, and Integrative Functional Phenotypes in COVID-19 Survivors - Effect of Fenofibrate
University of Pennsylvania
NCT05080192
Prognostication of Recovery in Early Disorders of Consciousness After COVID-19
Massachusetts General Hospital
NCT04476589
Implementation of COVID-19 Testing Strategies in Community Health Centers
Massachusetts General Hospital
NCT04802187
Contrast Enhanced Ultrasound in COVID-19
Children's Hospital of Philadelphia
NCT04640038
Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19
Memorial Sloan Kettering Cancer Center
NCT04824443
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 9 |
| Phase 2 | 13 |
| Phase 3 | 9 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Covid19 Trial Landscape
ClinicalTrials.gov lists 90 US studies indexed under Covid19, and 11 of those are currently open to recruitment — roughly 12% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Covid19 shows 11 late-stage studies (Phase 3 and Phase 4 combined) alongside 22 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Covid19 is led by Massachusetts General Hospital with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 90 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Covid19?
PlainTrial tracks 90 US clinical trials for Covid19, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Covid19?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.