Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Couples: early-phase trial registry
2 of 6 indexed Couples trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 2 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Couples: 6 US clinical trials tracked, 2 recruiting.
Couples is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 2 of these trials.
Enrollment posture brief
Registry condition couples
OPEN 2 | RECR 33% | LATE 0 | EARLY 1 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)
Couples lists 2 open slots (33% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Couples on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Couples is recruiting below its size-band peers.
2 of 6 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Couples research.
Medical University of South Carolina accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Couples enrolment sits around 192 participants.
Median target enrolment is 192 among the 6 trials that report a genuine target (sentinel values excluded). 2 of those (33.3%) plan for fewer than 100 participants.
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Couples research is mostly interventional.
6 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship
Medical University of South Carolina
NCT05786157
A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers
Massachusetts General Hospital
NCT06172907
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
University of Utah
NCT04845542
TYRO Couples Project Study
Midwest Evaluation & Research
NCT05267236
Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
Medical University of South Carolina
NCT03846505
Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder
University of Wisconsin, Madison
NCT04059549
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Couples records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Couples trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Couples page
6 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Couples trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Medical University of South Carolina sponsors the most Couples trials on record, review their full trial history before evaluating a specific study. See Medical University of South Carolina's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Couples condition card totals 6 registered trials; most-linked intervention A-CHESS; top US site state South Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.