Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 6 recruiting now official registry

Breast Cancer Stage IV clinical trials

6 of 11 indexed Breast Cancer Stage IV trials are currently recruiting.

11 US clinical trials · 6 currently recruiting

Breast Cancer Stage IV is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 5 of these trials.

The research picture

Breast Cancer Stage IV has 11 registered US clinical trials, 6 of them open to new participants right now, about 55% of the total.

6
recruiting participants now
55%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
5
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 14Phase 24

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING Phase 2 60 participants

HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission

Memorial Sloan Kettering Cancer Center

NCT07459673

RECRUITING Phase 1 48 participants

A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer

MBQ Pharma

NCT06075810

RECRUITING Phase 1 30 participants

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06246968

RECRUITING Phase 1 28 participants

A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT06678269

RECRUITING Phase 1 24 participants

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

General Oncology

NCT04150042

ACTIVE NOT RECRUITING 125 participants

Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study

Medical College of Wisconsin

NCT06234488

ACTIVE NOT RECRUITING 23 participants

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Memorial Sloan Kettering Cancer Center

NCT05036252

ACTIVE NOT RECRUITING Phase 2 15 participants

Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT05090358

ACTIVE NOT RECRUITING Phase 2 5 participants

Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer

Baylor Breast Care Center

NCT03324425

COMPLETED 68 participants

Quantitation of Endothelial Progenitor Cells as Markers of Tumor Angiogenesis in Breast Cancer

Indiana University School of Medicine

NCT00393341

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Breast Cancer Stage IV Trial Landscape

11 indexed Breast Cancer Stage IV studies · 6 recruiting (55%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (5 trials), 6 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer Stage IV?

PlainTrial tracks 11 US clinical trials for Breast Cancer Stage IV, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer Stage IV?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.