Is this data current?

Data is from ClinicalTrials.gov. Trial status may have changed. Always verify at ClinicalTrials.gov before making participation decisions.

Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 1 recruiting now early-phase tilt small index

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder): early-phase trial registry

Q: How many clinical trials are there for Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)?

PlainTrial tracks 1 US clinical trials for Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder), of which 1 are currently recruiting.

Q: Which interventions appear most often on Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) trial records?

NIO752 is the most-linked intervention name on Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) records (1 trial links), followed by Placebo. Names are sponsor-reported on ClinicalTrials.gov.

Q: How do I find a recruiting trial for Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)?

Use the trial list filtered by Recruiting status, or visit the trial finder to search by condition and state. Always discuss with your healthcare provider.

Compiled by PlainTrial · August 8, 2026

1 of 1 indexed Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #11,370 of 28,707 conditions by registered trial count.

Jump to open trials → Trial finder

1 US clinical trials · 1 currently recruiting · #11,370 of 28,707 conditions by registered trial count

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder): 1 US clinical trial tracked, 1 recruiting.

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) is the subject of 1 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University College, London, running 1 of these trials.

Enrollment posture brief

Registry condition autosomal-dominant-alzheimer-disease-due-to-mutation-of-presenilin-1-disorder

Volume-matched condition peers

Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)

Open-enrollment share among volume-matched conditions near Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) lists 1 open slots (100% of 1 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) is recruiting above its size-band peers.

1 of 1 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Open and recent trials

1 total, page 1 of 1

RECRUITING Phase 1 10 participants

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

University College, London

NCT06372821

Phase Distribution

Phase	Trial count
Phase 1	1

Top Sponsors

University College, London 1 trials

Named interventions

Most-linked intervention names on Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

NIO752 Drug

1 trials

Placebo Other

1 trials

US sites by state

Facility locations filed on Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) trials. A trial with sites in several states counts in each.

Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) page

1 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

1 Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
University College, London sponsors the most Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) trials on record, review their full trial history before evaluating a specific study. See University College, London's trials
Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) condition card totals 1 registered trials; most-linked intervention NIO752; top US site state Missouri. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.