Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Recurrent Craniopharyngioma 1
Recurrent Cubital Tunnel Syndrome 1
Recurrent Cutaneous Melanoma 3
Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck 3
Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma 3
Recurrent Dedifferentiated Liposarcoma 3
Recurrent Depression 1
Recurrent Desmoid Fibromatosis 2
Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant 1
Recurrent Diffuse Intrinsic Pontine Glioma 6
Recurrent Diffuse Large B-Cell Lymphoma 44
Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type 3
Recurrent Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation 2
Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type 4
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified 9
Recurrent Diffuse Midline Glioma, H3 K27-Altered 1
Recurrent Diffuse Midline Glioma, H3 K27M-Mutant 1
Recurrent Digestive System Neuroendocrine Tumor G1 1
Recurrent DIPG 1
Recurrent Disease 2
Recurrent Dislocation of Shoulder Region 1
Recurrent Distal Bile Duct Adenocarcinoma 1
Recurrent EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified 2
Recurrent Ectomesenchymoma 1
Recurrent Endometrial Adenocarcinoma 2
Recurrent Endometrial Cancer 3
Recurrent Endometrial Carcinoma 20
Recurrent Endometrial Clear Cell Adenocarcinoma 3
Recurrent Endometrial Dedifferentiated Carcinoma 1
Recurrent Endometrial Endometrioid Adenocarcinoma 5
Recurrent Endometrial Low Grade Endometrioid Adenocarcinoma 1
Recurrent Endometrial Mixed Cell Adenocarcinoma 1
Recurrent Endometrial Serous Adenocarcinoma 4
Recurrent Endometrial Undifferentiated Carcinoma 1
Recurrent Enteropathy-Associated T-Cell Lymphoma 1
Recurrent Ependymal Tumor 1
Recurrent Ependymoma 8
Recurrent Epithelial Cancer of Ovary 1
Recurrent Epithelial Ovarian Cancer 1
Recurrent Epithelial Ovarian Cancer Which Includes Epithelial Ovarian, Fallopian Tube and/or Primary Peritoneal Cancer 1
Recurrent Epithelioid Sarcoma 1
Recurrent Esophageal Adenocarcinoma 2
Recurrent Esophageal Cancer 2
Recurrent Esophageal Carcinoma 1
Recurrent Esophageal Squamous Cell Carcinoma 2
Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity 2
Recurrent Ewing Sarcoma 10
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor 7
Recurrent Extensive Stage Lung Small Cell Carcinoma 2
Recurrent Extensive Stage Small Cell Lung Carcinoma 1