Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations 1
Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation 1
Advanced or Metastatic Renal Cell Carcinoma 1
Advanced or Metastatic Solid Tumor 1
Advanced or Metastatic Solid Tumor Malignancies 2
Advanced or Metastatic Solid Tumors 20
Advanced or Metastatic Solid Tumors in Patients With Hepatic Impairment 1
Advanced or Metastatic Treatment-refractory Solid Tumor Malignancies 1
Advanced Oral Cavity Squamous Cell Carcinoma 1
Advanced Oropharyngeal Squamous Cell Carcinoma 1
Advanced Osteosarcoma 2
Advanced Ovarian Cancer 4
Advanced Ovarian Carcinoma 11
Advanced Ovarian Carcinosarcoma 1
Advanced Ovarian Clear Cell Adenocarcinoma 2
Advanced Ovarian Endometrioid Adenocarcinoma 1
Advanced Ovarian High Grade Serous Adenocarcinoma 1
Advanced Pancreatic Adenocarcinoma 8
Advanced Pancreatic Cancer 8
Advanced Pancreatic Carcinoma 4
Advanced Pancreatic Ductal Adenocarcinoma 5
Advanced Papillary Renal Cell Carcinoma 1
Advanced Paraganglioma 1
Advanced Parkinson's Disease 4
Advanced Peritoneal Malignant Mesothelioma 1
Advanced Pheochromocytoma and Paraganglioma 1
Advanced Pleural Malignant Mesothelioma 1
Advanced Primary Cutaneous T-Cell Non-Hodgkin Lymphoma 1
Advanced Primary Peritoneal Carcinoma 5
Advanced Primary Peritoneal High Grade Serous Adenocarcinoma 1
Advanced Prostate Adenocarcinoma 2
Advanced Prostate Adenocarcinoma With Neuroendocrine Differentiation 1
Advanced Prostate Cancer 7
Advanced Prostate Carcinoma 6
Advanced Rare Malignant Solid Neoplasm 1
Advanced Rectal Cancer 1
Advanced Refractory Left Ventricular Heart Failure 1
Advanced Refractory Solid Tumors 1
Advanced Relapsed or Refractory Endometrial Cancer 1
Advanced Relapsed or Refractory Germ Cell Tumours 1
Advanced Relapsed or Refractory Ovarian Cancer 1
Advanced Relapsed Tumors 1
Advanced Renal Cell Carcinoma 13
Advanced Renal Cell Carcinoma (aRCC) 2
Advanced Renal Cell Carcinoma (RCC) 1
Advanced Renal Pelvis Urothelial Carcinoma 1
Advanced Retinitis Pigmentosa 1
Advanced Rheumatoid Arthritis 1
Advanced Salivary Gland Carcinoma 2
Advanced Sarcoma 2