Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Advanced Malignant Solid Tumor 4
Advanced Malignant Solid Tumors 3
Advanced Malignant Thoracic Neoplasm 1
Advanced Malignant Tumors 1
Advanced MDS 1
Advanced Medical Illness 1
Advanced Melanoma 22
Advanced Melanoma and Normal or Impaired 1
Advanced Merkel Cell Carcinoma 1
Advanced Mesothelioma 1
Advanced Metastatic (Stage IV) Colorectal Cancer 1
Advanced Metastatic Cancer 1
Advanced Metastatic Castration Resistant Prostate Cancer 2
Advanced Metastatic Clear Cell Renal Cell Carcinoma (CCRCC) 1
Advanced Metastatic Colorectal Cancer 1
Advanced Microsatellite Stable Colorectal Carcinoma 3
Advanced MTAP-null Solid Tumors 1
Advanced Mucosal Melanoma 1
Advanced Mycosis Fungoides 1
Advanced Myeloproliferative Disease 1
Advanced Myeloproliferative Neoplasms 1
Advanced Neoplasms 1
Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation 1
Advanced Non-Small Cell Squamous Lung Cancer 2
Advanced Non-Small-Cell Lung Cancer 23
Advanced Non-squamous Non-small-cell Lung Cancer 3
Advanced Nonhematologic Malignancies 1
Advanced NSCLC 3
Advanced NUT Carcinoma 1
Advanced or Inoperable Gastric Cancer 1
Advanced or Metastatic Adrenocortical Carcinoma 1
Advanced or Metastatic Breast Cancer 4
Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC) 1
Advanced or Metastatic Colorectal Cancer 1
Advanced or Metastatic CRC 1
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) 1
Advanced or Metastatic Gastric Cancer 1
Advanced or Metastatic Gastroesophageal Junction Cancer 1
Advanced or Metastatic KRAS-mutant Tumor 1
Advanced or Metastatic KRAS-mutant Tumor in Colorectal Cancer 1
Advanced or Metastatic KRAS-mutant Tumor in Non Small Cell Lung Cancer 1
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma 1
Advanced Or Metastatic Merkel Cell Carcinoma 2
Advanced or Metastatic MTAP-deleted Solid Tumors 1
Advanced or Metastatic Non-clear Cell Renal Cell Carcinoma 1
Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) 2
Advanced or Metastatic Non-Small-Cell Lung Cancer 4
Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer 1
Advanced or Metastatic NRAS-mutant Melanoma 1
Advanced or Metastatic NSCLC 2