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NCT07680517 · ClinicalTrials.gov registry record · NA

Examining the Efficacy of Short-Term Intensive PTSD Treatment on Psychological and Cognitive Impairment Symptoms

A NA study, sponsored by Ohio State University.

Recruiting
Registry status
NA
Development phase
120
Enrollment target

NCT07680517: Recruiting NA study, sponsored by Ohio State University.

NCT07680517 is a NA study that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 120 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07680517, a NA study, is actively recruiting participants, sponsored by Ohio State University.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target

Study Summary

Our long-term goal is to provide rapid and sustained reductions of trauma and cognitive-related symptoms among Special Operations personnel with PTSD or subthreshold PTSD. The primary objective of this project is to examine the effectiveness of massed PTSD treatment (i.e., CPT and EMDR) in "real-world" military settings. CPT and EMDR are both empirically supported psychotherapies for PTSD. To accomplish this objective, we will enroll military personnel meeting diagnostic criteria for PTSD or subthreshold PTSD (i.e., meeting threshold levels for 3 of 4 symptom criteria).

Primary Outcome

Good end-state is defined as (a) a score on the PCL-5 ≤ 19 and (b) mutual agreement by the patient and therapist that the patient has achieved the therapy's goals. The PCL-5 is a validated self-report scale that assesses the severity of DSM-5-defined PTSD symptoms within the past week. 28 Items are summed so that higher scores reflect greater symptom severity. Previous research shows that over 94% of military personnel with good end-state following trauma-focused therapy had clinically meaningfu

Interventions

  • BEHAVIORAL Cognitive Processing Therapy
  • BEHAVIORAL Eye-Movement Desensitization and Reprocessing

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2026-04-01
Est. Completion 2028-08
Phase NA
Ohio State University

552 total trials

What NCT07680517 shows while recruiting

NCT07680517 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 2 interventions - of which Cognitive Processing Therapy is the first listed.

NCT07680517 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07680517 about?

NCT07680517 is a clinical study titled "Examining the Efficacy of Short-Term Intensive PTSD Treatment on Psychological and Cognitive Impairment Symptoms". Our long-term goal is to provide rapid and sustained reductions of trauma and cognitive-related symptoms among Special Operations personnel with PTSD or subthreshold PTSD. The primary objective of this project is to examine the effectiveness of massed PTSD treatment (i.e., CPT and EMDR) in "real-wor...

What is the current status of trial NCT07680517?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2026-04-01. Estimated completion is 2028-08.

What interventions are being tested in trial NCT07680517?

The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), Eye-Movement Desensitization and Reprocessing (BEHAVIORAL).

Who is sponsoring clinical trial NCT07680517?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07680517's enrollment target sits among peer trials

120 762nd of 2000 higher than 1,198 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07680517, the US trial registry maintained by the National Library of Medicine. NCT07680517 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.