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NCT07673328 · ClinicalTrials.gov registry record · NA
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal
A NA study, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 65
- Enrollment target
NCT07673328: Recruiting NA study, sponsored by University of Michigan.
NCT07673328 is a NA study that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 65 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07673328, a NA study, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 65 participants
- Enrollment target
Study Summary
The overall goal of this project is to establish a novel design and control paradigm for modular, partial-assist powered orthoses (exoskeletons) to enhance voluntary lower-limb motion and manage pain in broad patient populations. Building upon a previous study period that addressed weakness from advanced age or muscle fatigue, this current period extends the technology to novel powered unloader orthoses designed to manage knee osteoarthritis (OA) pain. The investigators hypothesize that by providing 15-30% of biological joint torque, these motorized devices can reduce muscular contributions to painful loads on the joint's surfaces during activities of daily living (ADLs). The project aims to develop a task-agnostic, neural network-based controller and establish the feasibility of reducing knee pain and muscle effort in individuals with multi-compartment knee osteoarthritis.
Primary Outcome
Muscle activity will be measured by surface EMG electrodes, and EMG sites will be averaged by flexors and extensors. For each condition (no orthosis vs. powered orthosis), signals will be normalized by their peaks during the no-orthosis condition, and then averaged over cycle, repetitions, and tasks to obtain overall muscle effort (focusing on knee extension for the powered knee orthosis, hip extension and flexion for the powered hip orthosis, and ankle plantarflexion for the powered ankle ortho
Interventions
- DEVICE Modular powered orthosis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2025-07-18 |
| Est. Completion | 2030-03-31 |
| Phase | NA |
What NCT07673328 shows while recruiting
NCT07673328 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Modular powered orthosis is the first listed.
NCT07673328 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07673328 about?
NCT07673328 is a clinical study titled "Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal". The overall goal of this project is to establish a novel design and control paradigm for modular, partial-assist powered orthoses (exoskeletons) to enhance voluntary lower-limb motion and manage pain in broad patient populations. Building upon a previous study period that addressed weakness from adv...
What is the current status of trial NCT07673328?
This trial is currently recruiting. It is a NA study. The enrollment target is 65 participants. The study started on 2025-07-18. Estimated completion is 2030-03-31.
What interventions are being tested in trial NCT07673328?
The interventions under investigation include: Modular powered orthosis (DEVICE).
Who is sponsoring clinical trial NCT07673328?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07673328's enrollment target sits among peer trials
65 1144th of 2000 higher than 854 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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