Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07666165 · ClinicalTrials.gov registry record · NA

Functional Neuroimaging and Motor Recovery After Stroke

A NA study, sponsored by University of Delaware.

Completed
Registry status
NA
Development phase
14
Enrollment target

NCT07666165: Completed NA study, sponsored by University of Delaware.

NCT07666165 is a NA study that has completed, run by University of Delaware. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07666165, a NA study, has completed, sponsored by University of Delaware.

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

The primary goal of this project is to establish whether fMRI measurements of brain connectivity measured before and after interaction with a sensorimotor task can predict subsequent training-induced gains in motor function in a population of individuals with chronic stroke. This study involves individuals with chronic motor impairment resulting from stroke. The procedures include one fMRI session (baseline), followed by twelve training visits (2 or 3 times per week over 4-5 weeks) focused on training motor function of the hand and wrist conducted with a physical therapist. During imaging, participants interact with an MRI-compatible joystick that will cue participants to move their wrist in a controlled way. Before and after the training program, subjects will undergo behavioral testing with a physical therapist to quantify changes in clinical measures of impairment.

Primary Outcome

The primary outcome is the goodness of fit (R\^2) of a regression model relating brain connectivity measures (predictors) to gains in motor function after stroke (clinical measurement). Predictors: resting-state functional connectivity measured using resting-state fMRI (rs-fMRI). Connectivity is quantified as Fisher-transformed correlation coefficients (z scores, unitless) of signal measured in pairs of regions (edges) within the cortico-thalamic-cerebellar network. Predictors include baseline

Interventions

  • BEHAVIORAL Conventional Physical Therapy Intervention

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2022-01-25
Est. Completion 2022-12-22
Phase NA
University of Delaware

106 total trials

What the finished NCT07666165 record still lists

NCT07666165 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Conventional Physical Therapy Intervention is the first listed.

NCT07666165 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07666165 about?

NCT07666165 is a clinical study titled "Functional Neuroimaging and Motor Recovery After Stroke". The primary goal of this project is to establish whether fMRI measurements of brain connectivity measured before and after interaction with a sensorimotor task can predict subsequent training-induced gains in motor function in a population of individuals with chronic stroke. This study involves ind...

What is the current status of trial NCT07666165?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2022-01-25. Estimated completion is 2022-12-22.

What interventions are being tested in trial NCT07666165?

The interventions under investigation include: Conventional Physical Therapy Intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT07666165?

This trial is sponsored by University of Delaware, which has 106 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07666165's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02523092 · 14 participants · Phase 4

    Use of CXCL9 as a Biomarker of Acthar Efficacy

  • NCT04263285 · 14 participants · NA

    Treatment of Depression Post-SCI

  • NCT04743271 · 14 participants · NA

    Food and Circadian Timing

  • NCT05065671 · 14 participants · Phase 1

    Microbiome Derived Metabolism and Pharmacokinetics

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT06358040 · started 2026-10 · NA

    Opioid Dispenser for Microdiscectomy/Laminectomy

Source: ClinicalTrials.gov NCT07666165, the US trial registry maintained by the National Library of Medicine. NCT07666165 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.