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NCT07664995 · ClinicalTrials.gov registry record · NA
Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation
A NA study, sponsored by University of Illinois at Chicago.
- Not yet
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT07664995: Clinical Trial NA study, sponsored by University of Illinois at Chicago.
NCT07664995 is a NA study that has not yet begun recruiting, run by University of Illinois at Chicago. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07664995, a NA study, has not yet begun recruiting, sponsored by University of Illinois at Chicago.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to learn if ischemic conditioning and neuromuscular electrical stimulation improves muscle strength and walking behavior in those with limb loss. The main questions this trial aims to answer are: Does neuromuscular electrical stimulation improve muscle strength and gait behavior in people who have a leg amputation? Does neuromuscular electrical stimulation boost the effects of ischemic conditioning on muscle strength and gait behavior in people who have a leg amputation? Researchers will compare the effects of neuromuscular electrical stimulation to ischemic conditioning to see if there are any significant differences between the impacts of each intervention. Also, researchers will use both interventions together to see if the interventions can boost each other's positive impacts on walking and function in people with leg amputation. Participants will: * Do ischemic conditioning OR neuromuscular electrical stimulation OR both interventions at home every other day for 2 weeks * Visit the laboratory before and after completing interventions for the tests * Visit the laboratory one week after the post intervention visit for follow-up tests
Primary Outcome
Participants will be asked to walk at their self-selected gait speed (m/s) for 6 minutes on a split-belt treadmill at the 1st, 9th, and 10th visits. The change in gait speed from the first visit will be calculated by SPSS v. 31.0
Interventions
- DEVICE Blood pressure cuff
- DEVICE Neuromuscular Electrical Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2027-12 |
| Phase | NA |
What is known before NCT07664995 opens enrollment
NCT07664995 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Blood pressure cuff is the first listed.
NCT07664995 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07664995 about?
NCT07664995 is a clinical study titled "Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation". The goal of this clinical trial is to learn if ischemic conditioning and neuromuscular electrical stimulation improves muscle strength and walking behavior in those with limb loss. The main questions this trial aims to answer are: Does neuromuscular electrical stimulation improve muscle strength an...
What is the current status of trial NCT07664995?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2026-07-01. Estimated completion is 2027-12.
What interventions are being tested in trial NCT07664995?
The interventions under investigation include: Blood pressure cuff (DEVICE), Neuromuscular Electrical Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07664995?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07664995's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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