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NCT07662083 · ClinicalTrials.gov registry record · NA
Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C
A NA study, sponsored by West Virginia University.
- Not yet
- Registry status
- NA
- Development phase
- 80
- Enrollment target
NCT07662083: Clinical Trial NA study, sponsored by West Virginia University.
NCT07662083 is a NA study that has not yet begun recruiting, run by West Virginia University. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07662083, a NA study, has not yet begun recruiting, sponsored by West Virginia University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
Study Summary
This study evaluates the efficacy and safety of transcutaneous auricular vagus nerve stimulation (ta-VNS) in adults with constipation-predominant irritable bowel syndrome (IBS-C). Participants will be randomized to receive either active or sham stimulation using a non-invasive auricular device over a 60-day period. The primary objectives are to assess changes in symptom severity and quality of life using validated instruments, including the IBS Symptom Severity Scale (IBS-SSS) and the IBS Quality of Life questionnaire (IBS-QOL). Secondary assessments include safety and participant compliance. This study aims to determine whether ta-VNS is an effective non-invasive therapeutic modality for improving symptoms and quality of life in patients with IBS-C.
Primary Outcome
Evaluate the effect of transcutaneous auricular vagus nerve stimulation (ta-VNS) on symptom severity in patients with IBS-C using the IBS Symptom Severity Scale (IBS-SSS). The IBS-SSS assesses abdominal pain severity and frequency, abdominal distension, bowel habit satisfaction, and interference with quality of life. Scores range from 0 to 500, with higher scores indicating more severe symptoms (≤75 remission, 75-174 mild, 175-299 moderate, 300-500 severe). The outcome measure is defined as the
Interventions
- DEVICE Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS)
- DEVICE Sham Transcutaneous Auricular Vagus Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2026-07 |
| Est. Completion | 2027-07 |
| Phase | NA |
What is known before NCT07662083 opens enrollment
NCT07662083 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS) is the first listed.
NCT07662083 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07662083 about?
NCT07662083 is a clinical study titled "Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C". This study evaluates the efficacy and safety of transcutaneous auricular vagus nerve stimulation (ta-VNS) in adults with constipation-predominant irritable bowel syndrome (IBS-C). Participants will be randomized to receive either active or sham stimulation using a non-invasive auricular device over ...
What is the current status of trial NCT07662083?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2026-07. Estimated completion is 2027-07.
What interventions are being tested in trial NCT07662083?
The interventions under investigation include: Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS) (DEVICE), Sham Transcutaneous Auricular Vagus Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07662083?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07662083's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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