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NCT07635017 · ClinicalTrials.gov registry record · NA
Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation
A NA study, sponsored by Carnegie Mellon University.
- Not yet
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT07635017 is a NA study that has not yet begun recruiting, run by Carnegie Mellon University. The registered enrollment target is 25 participants.
The verdict
NCT07635017, a NA study, has not yet begun recruiting, sponsored by Carnegie Mellon University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain activity, and whether combining them produces stronger or more consistent effects than either one used alone. The motivation for this comes from the observation that TMS, which is FDA-approved for treating depression, tends to work less well in postmenopausal women because lower estrogen levels reduce the brain's ability to respond to stimulation. The research team believes that pairing TMS with TES, which targets a different set of brain cells, may be able to overcome this hormonal barrier and make stimulation more effective. Participants will come into the lab for up to 24 visits over 8 months, beginning with an initial visit to establish the right stimulation settings, followed by a series of stimulation sessions in which brain activity is measured before and after receiving either TES, TMS, or both together. For female participants, sessions will be scheduled at specific points in the menstrual cycle to capture the natural monthly rise and fall of estrogen, while male participants will be scheduled on a comparable fixed interval as a comparison group. The insights gained from this study could directly inform the development of better, more reliable brain stimulation treatments for women with depression.
Interventions
- DEVICE Transcranial Magnetic Stimulation
- DEVICE Transcranial Electrical Stimulation
- DEVICE TES + TMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2028-07-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07635017
The ClinicalTrials.gov registry entry for NCT07635017 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Carnegie Mellon University, which has 37 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Transcranial Magnetic Stimulation is the first listed.
NCT07635017 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07635017 about?
NCT07635017 is a clinical study titled "Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation". This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain activity, and whether combining them produces stronger or more consistent effects than either one used alone. The motivatio...
What is the current status of trial NCT07635017?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2026-07-01. Estimated completion is 2028-07-01.
What interventions are being tested in trial NCT07635017?
The interventions under investigation include: Transcranial Magnetic Stimulation (DEVICE), Transcranial Electrical Stimulation (DEVICE), TES + TMS (DEVICE).
Who is sponsoring clinical trial NCT07635017?
This trial is sponsored by Carnegie Mellon University, which has 37 total clinical trials registered on ClinicalTrials.gov.
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