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NCT07594015 · ClinicalTrials.gov registry record · Phase 2

Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Failure of First-Line Therapy With Platinum-based Doublet and Immunotherapy

A Phase 2 study, sponsored by University of Miami.

Recruiting
Registry status
Phase 2
Development phase
46
Enrollment target

NCT07594015 is a Phase 2 study that is actively recruiting participants, run by University of Miami. The registered enrollment target is 46 participants.

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The verdict

NCT07594015, a Phase 2 study, is actively recruiting participants, sponsored by University of Miami.

RECRUITING
Registry status
Phase 2
Development phase
46 participants
Enrollment target

Study Summary

The purpose of this study is to determine the efficacy and safety of Pembrolizumab in combination with Lenvatinib in recurrent, mismatch repair-proficient endometrial cancer after failure of first-line therapy with a platinum-based doublet chemotherapy and immunotherapy.

Interventions

  • DRUG Pembrolizumab
  • DRUG Lenvatinib

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2026-06-01
Est. Completion 2031-06-01
Phase Phase 2

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT07594015

The ClinicalTrials.gov registry entry for NCT07594015 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT07594015 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07594015 about?

NCT07594015 is a clinical study titled "Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Failure of First-Line Therapy With Platinum-based Doublet and Immunotherapy". The purpose of this study is to determine the efficacy and safety of Pembrolizumab in combination with Lenvatinib in recurrent, mismatch repair-proficient endometrial cancer after failure of first-line therapy with a platinum-based doublet chemotherapy and immunotherapy.

What is the current status of trial NCT07594015?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2026-06-01. Estimated completion is 2031-06-01.

What interventions are being tested in trial NCT07594015?

The interventions under investigation include: Pembrolizumab (DRUG), Lenvatinib (DRUG).

Who is sponsoring clinical trial NCT07594015?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.