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NCT07577856 · ClinicalTrials.gov registry record · Phase 3

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

A Phase 3 study, sponsored by Janssen Research & Development.

Recruiting
Registry status
Phase 3
Development phase
644
Enrollment target

NCT07577856 is a Phase 3 study that is actively recruiting participants, run by Janssen Research & Development. The registered enrollment target is 644 participants.

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The verdict

NCT07577856, a Phase 3 study, is actively recruiting participants, sponsored by Janssen Research & Development.

RECRUITING
Registry status
Phase 3
Development phase
644 participants
Enrollment target

Study Summary

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the colon becomes inflamed and develops ulcers).

Interventions

  • DRUG Guselkumab
  • DRUG JNJ-78934804

Trial Details

FieldValue
Enrollment Target 644 participants
Start Date 2026-05-23
Est. Completion 2030-10-30
Phase Phase 3

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT07577856

The ClinicalTrials.gov registry entry for NCT07577856 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 644 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Guselkumab is the first listed.

NCT07577856 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07577856 about?

NCT07577856 is a clinical study titled "A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis". The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the colon becomes ...

What is the current status of trial NCT07577856?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 644 participants. The study started on 2026-05-23. Estimated completion is 2030-10-30.

What interventions are being tested in trial NCT07577856?

The interventions under investigation include: Guselkumab (DRUG), JNJ-78934804 (DRUG).

Who is sponsoring clinical trial NCT07577856?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.