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NCT07526545 · ClinicalTrials.gov registry record · NA
Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial
A NA study, sponsored by University of Michigan Rogel Cancer Center.
- Not yet
- Registry status
- NA
- Development phase
- 800
- Enrollment target
NCT07526545: Clinical Trial NA study, sponsored by University of Michigan Rogel Cancer Center.
NCT07526545 is a NA study that has not yet begun recruiting, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 800 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07526545, a NA study, has not yet begun recruiting, sponsored by University of Michigan Rogel Cancer Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 800 participants
- Enrollment target
Study Summary
This clinical trial tests how well a urine prostate cancer screening test, My Prostate Score 2 (MPS2), integrated with magnetic resonance imaging (MRI) works for early detection of prostate cancer. MPS2 is an investigational urine-based test designed to help identify the likelihood of having aggressive prostate cancer. MPS2 testing works by measuring specific early detection biomarkers that include genetic information. This next-generation test aims to address a major challenge in prostate cancer care-detecting only the cancers that truly need treatment. Results may lead to paradigm shifts in early detection algorithms and reduce reliance on MRI and biopsy.
Primary Outcome
Will compare the proportions of patients with detected csPCa in the intervention and control arms (p1 and p2, respectively) using the OBrien Fleming stopping boundaries which control the overall one-sided Type I error rate to be less than .10.
Interventions
- PROCEDURE Magnetic Resonance Imaging
- PROCEDURE Biopsy Procedure
- OTHER Electronic Health Record Review
- DEVICE Diagnostic Procedure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2026-09-01 |
| Est. Completion | 2030-03-01 |
| Phase | NA |
What is known before NCT07526545 opens enrollment
NCT07526545 is an interventional study that assigns participants to a tested intervention. The registered 800 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 4 interventions - of which Magnetic Resonance Imaging is the first listed.
NCT07526545 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07526545 about?
NCT07526545 is a clinical study titled "Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial". This clinical trial tests how well a urine prostate cancer screening test, My Prostate Score 2 (MPS2), integrated with magnetic resonance imaging (MRI) works for early detection of prostate cancer. MPS2 is an investigational urine-based test designed to help identify the likelihood of having aggress...
What is the current status of trial NCT07526545?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 800 participants. The study started on 2026-09-01. Estimated completion is 2030-03-01.
What interventions are being tested in trial NCT07526545?
The interventions under investigation include: Magnetic Resonance Imaging (PROCEDURE), Biopsy Procedure (PROCEDURE), Electronic Health Record Review (OTHER), Diagnostic Procedure (DEVICE).
Who is sponsoring clinical trial NCT07526545?
This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07526545's enrollment target sits among peer trials
800 135th of 2000 higher than 1,861 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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