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NCT07525193 · ClinicalTrials.gov registry record · NA

PREnatal Choline and Infant Outcomes Study

A NA study, sponsored by East Carolina University.

Recruiting
Registry status
NA
Development phase
102
Enrollment target

NCT07525193: Recruiting NA study, sponsored by East Carolina University.

NCT07525193 is a NA study that is actively recruiting participants, run by East Carolina University. The registered enrollment target is 102 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07525193, a NA study, is actively recruiting participants, sponsored by East Carolina University.

RECRUITING
Registry status
NA
Development phase
102 participants
Enrollment target

Study Summary

Less than 10% of pregnant women consume adequate levels of choline, an essential nutrient for maternal lipid metabolism, placental efficiency, and fetal development. Most prenatal vitamins do not contain choline; a research survey shows that only 6% of OB/GYNs were likely to recommend choline-rich foods to pregnant women. Nutrition education grounded in the Health Belief Model (HBM) has high efficacy among pregnant women; therefore, it is likely that HBM-driven choline education intervention will increase maternal choline levels. No studies have evaluated the influence of prenatal choline education intervention on maternal, placental, and neonatal outcomes. Our preliminary data suggest that increased choline intake corresponds with lower maternal body fat percentage (BF%), infant 1-month BF%, and MSC lipid accumulation, as well as increased placental efficiency. The central hypothesis is that choline education will increase maternal choline levels and improve placental function and infant health. We will test this hypothesis with three aims: to determine the influence of choline education intervention on maternal choline intake, placental efficiency, and infant health at the whole-body and cellular levels. The proposed study will be the first to provide a critical translational understanding of the influence of prenatal choline education intervention on maternal, placental, and child health.

Primary Outcome

Multiple 24-hour dietary recalls

Interventions

  • BEHAVIORAL Choline nutrition education (CNE)

Trial Details

FieldValue
Enrollment Target 102 participants
Start Date 2025-05-15
Est. Completion 2027-05-14
Phase NA
East Carolina University

58 total trials

What NCT07525193 shows while recruiting

NCT07525193 is an interventional study that assigns participants to a tested intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which Choline nutrition education (CNE) is the first listed.

NCT07525193 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07525193 about?

NCT07525193 is a clinical study titled "PREnatal Choline and Infant Outcomes Study". Less than 10% of pregnant women consume adequate levels of choline, an essential nutrient for maternal lipid metabolism, placental efficiency, and fetal development. Most prenatal vitamins do not contain choline; a research survey shows that only 6% of OB/GYNs were likely to recommend choline-rich f...

What is the current status of trial NCT07525193?

This trial is currently recruiting. It is a NA study. The enrollment target is 102 participants. The study started on 2025-05-15. Estimated completion is 2027-05-14.

What interventions are being tested in trial NCT07525193?

The interventions under investigation include: Choline nutrition education (CNE) (BEHAVIORAL).

Who is sponsoring clinical trial NCT07525193?

This trial is sponsored by East Carolina University, which has 58 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07525193's enrollment target sits among peer trials

102 837th of 2000 higher than 1,161 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07525193, the US trial registry maintained by the National Library of Medicine. NCT07525193 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.