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NCT07503925 · ClinicalTrials.gov registry record · Phase 4

THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health

A Phase 4 study, sponsored by Ohio State University Comprehensive Cancer Center.

Not yet
Registry status
Phase 4
Development phase
15
Enrollment target

NCT07503925: Clinical Trial Phase 4 study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT07503925 is a Phase 4 study that has not yet begun recruiting, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 15 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07503925, a Phase 4 study, has not yet begun recruiting, sponsored by Ohio State University Comprehensive Cancer Center.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
15 participants
Enrollment target

Study Summary

Although nicotine pouches have been gaining popularity over the last few years, little known about how nicotine pouch users actually use these products. This study will be comprised of adults who use nicotine pouches. If eligible, participants will be asked to complete three study visits and participate in two switching periods where participants use study-provided nicotine pouches.

Primary Outcome

Nicotine delivery will be summarized by Cmax, the maximum nicotine concentration observed in the plasma samples for each participant.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Survey Administration
  • DRUG Nicotine Oral Pouch
  • OTHER Text Message-Based Navigation Intervention

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2026-07-01
Est. Completion 2027-12-31
Phase Phase 4

What is known before NCT07503925 opens enrollment

NCT07503925 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 4 interventions - of which Biospecimen Collection is the first listed.

NCT07503925 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07503925 about?

NCT07503925 is a clinical study titled "THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health". Although nicotine pouches have been gaining popularity over the last few years, little known about how nicotine pouch users actually use these products. This study will be comprised of adults who use nicotine pouches. If eligible, participants will be asked to complete three study visits and partic...

What is the current status of trial NCT07503925?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2026-07-01. Estimated completion is 2027-12-31.

What interventions are being tested in trial NCT07503925?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Nicotine Oral Pouch (DRUG), Text Message-Based Navigation Intervention (OTHER).

Who is sponsoring clinical trial NCT07503925?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07503925's enrollment target sits among peer trials

15 1880th of 2000 higher than 100 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07503925, the US trial registry maintained by the National Library of Medicine. NCT07503925 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.