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NCT07464886 · ClinicalTrials.gov registry record · Phase 3
Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth
A Phase 3 study of Mild Depression, sponsored by University of Cincinnati.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT07464886 is a Phase 3 study of Mild Depression that is actively recruiting participants, run by University of Cincinnati. The registered enrollment target is 160 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07464886, a Phase 3 study of Mild Depression, is actively recruiting participants, sponsored by University of Cincinnati.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment response in mildly depressed youth.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG N-acetylcysteine
- BEHAVIORAL Mindfulness-based cognitive therapy
- BEHAVIORAL Sham mindfulness-based intervention
Study Locations (1)
Ohio
- University of Cincinnati, Department of Psychiatry and Behavioral Neuroscience - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2026-02-26 |
| Est. Completion | 2030-12 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07464886
The ClinicalTrials.gov registry entry for NCT07464886 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Cincinnati, which has 245 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mild Depression appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT07464886 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT07464886 about?
NCT07464886 is a clinical study titled "Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth". The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment response in mildly depressed youth.
What is the current status of trial NCT07464886?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 160 participants. The study started on 2026-02-26. Estimated completion is 2030-12.
What conditions does trial NCT07464886 study?
This clinical trial studies the following conditions: Mild Depression.
What interventions are being tested in trial NCT07464886?
The interventions under investigation include: Placebo (DRUG), N-acetylcysteine (DRUG), Mindfulness-based cognitive therapy (BEHAVIORAL), Sham mindfulness-based intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT07464886?
This trial is sponsored by University of Cincinnati, which has 245 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07464886 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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