Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06586437 · ClinicalTrials.gov registry record · NA
Neuromodulation of the Cortex and Spinal Cord
A NA study of Cerebral Palsy, sponsored by Father Flanagan's Boys' Home.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06586437: Recruiting NA study of Cerebral Palsy, sponsored by Father Flanagan's Boys' Home.
NCT06586437 is a NA study of Cerebral Palsy that is actively recruiting participants, run by Father Flanagan's Boys' Home. The registered enrollment target is 50 participants, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06586437, a NA study of Cerebral Palsy, is actively recruiting participants, sponsored by Father Flanagan's Boys' Home.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Specific Aim 1: To further quantify the difference in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence of persons with CP. Overall hypotheses: The sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be uncharacteristic in persons with CP when compared with neurotypical controls. Furthermore, the extent of the alterations in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be tightly linked with the clinical presentations of persons with CP. Specific Aim 2: To investigate the effect of transcutaneous current stimulation applied over the cortex and/or spinal cord on the sensorimotor cortical activity, spinal cord dynamics, and corticospinal coherence. Overall hypotheses: Compared with the sham controls, those receiving the transcutaneous current stimulation will demonstrate alterations in the strength of the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence. Moreover, the extent of the alterations in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be tightly linked with the clinical presentations of persons with CP.
Primary Outcome
A stimulus intensity will be incrementally increased or decreased from 0.1 to 10 mA as the subject verbally reports their first sensation of the stimulus or perceived loss of the stimulus sensation. The ascending and descending perception tests will be repeated 3 times. The mean of the intensities will be used as the primary outcome variable. The KINARM robot will passively move the participant's hand-arm to various positions in the workspace as they hold the graspable robotic arm. The particip
Conditions Studied
Interventions
- BEHAVIORAL Clinical Assessments
- BEHAVIORAL Brain-Spinal Cord fMRI
- BEHAVIORAL Hoffmann Reflex Assessments
- BEHAVIORAL MEG Imaging
- BEHAVIORAL Transcutaneous Current Stimulation
Study Locations (1)
Nebraska
- Boys Town National Research Hospital - Boys Town
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-01-17 |
| Est. Completion | 2029-08 |
| Phase | NA |
What NCT06586437 shows while recruiting
NCT06586437 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 229-participant average among 91 other Cerebral Palsy trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Cerebral Palsy appearing as the primary indexed condition, and to 5 interventions - of which Clinical Assessments is the first listed.
NCT06586437 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT06586437 about?
NCT06586437 is a clinical study titled "Neuromodulation of the Cortex and Spinal Cord". Specific Aim 1: To further quantify the difference in the sensorimotor cortical activity, spinal cord activity, and corticospinal coherence of persons with CP. Overall hypotheses: The sensorimotor cortical activity, spinal cord activity, and corticospinal coherence will be uncharacteristic in perso...
What is the current status of trial NCT06586437?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-01-17. Estimated completion is 2029-08.
What conditions does trial NCT06586437 study?
This clinical trial studies the following conditions: Cerebral Palsy.
What interventions are being tested in trial NCT06586437?
The interventions under investigation include: Clinical Assessments (BEHAVIORAL), Brain-Spinal Cord fMRI (BEHAVIORAL), Hoffmann Reflex Assessments (BEHAVIORAL), MEG Imaging (BEHAVIORAL), Transcutaneous Current Stimulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06586437?
This trial is sponsored by Father Flanagan's Boys' Home, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06586437 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cerebral Palsy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06586437's enrollment target sits among peer trials
50 39th of 91 higher than 52 of 91 other Cerebral Palsy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cerebral Palsy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Motor Training for Infants With Cerebral Palsy
RECRUITING · NA
-
Implementation of Therapy Together
RECRUITING · NA
-
Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders
RECRUITING · NA
-
Em-power: Maximizing Functional Independence for Children With Severe Cerebral Palsy
RECRUITING · NA
-
Effectiveness of Robotic Gait Training and Physical Therapy for Children and Youth With Cerebral Palsy
RECRUITING · NA
-
Gait Adaptation and Biofeedback for Cerebral Palsy
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI